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A systematic review with meta-analysis of survival, quality of life and cost-effectiveness of home parenteral nutrition in patients with inoperable malignant bowel obstruction.
TLDR
This is the first health economic evaluation and systematic review of survival and QOL for patients with inoperable bowel obstruction receiving HPN during the palliative phase of malignancy and Meta-analyses reveal a short survival and health economic analysis demonstrates high associated costs. Expand
Taurolidine locks significantly reduce the incidence of catheter-related blood stream infections in high-risk patients on home parenteral nutrition
TLDR
Reductions in infections were identified in each smaller subgroup of patients receiving home parenteral nutrition, confirming previous reports of a significant reduction in infections when taurolidine is used as secondary prophylaxis and providing initial data suggesting the benefit of its use as primary proPHylaxis. Expand
Diagnostic accuracy of magnetic resonance enterography and small bowel ultrasound for the extent and activity of newly diagnosed and relapsed Crohn's disease (METRIC): a multicentre trial
TLDR
Both MRE and ultrasound have high sensitivity for detecting small bowel disease presence and both are valid first-line investigations, and viable alternatives to ileocolonoscopy. Expand
Compartment Syndrome: An Unusual Complication of Influenza AInfection
TLDR
A 43-year-old man who presented with 4-limb compartment syndrome secondary to influenza A myositis is discussed, to increase awareness of this potentially life-threatening complication. Expand
The successful treatment of IgG4-positive colitis with adalimumab in a patient with IgG4-related sclerosing disease--a new subtype of aggressive colitis?
TLDR
This is the first case to report both the effectiveness of adalimumab in treating IgG4 positive colitis in a patient with IgG 4-related sclerosing disease, and to prospectively record resolution of an IgG3 positive colonic infiltrate with immunosuppression. Expand
A case of adrenal infarction in a patient with COVID 19 infection
TLDR
The recent literature reviewing how Covid-19 creates a hypercoaguable state, with acute adrenal infarction as a possible prothrombotic complication, is discussed. Expand
EFFICACY OF HIGH AND LOW DOSE ORAL VITAMIN D REPLACEMENT THERAPY IN INFLAMMATORY BOWEL DISEASE (IBD): SINGLE CENTRE COHORT
TLDR
Oral vitamin D replacement is an effective treatment for vitamin D deficiency in IBD patients and appears to be dose responsive, in both Crohn's disease and ulcerative colitis patients. Expand
Meningitis in an adult caused by Hemophilus influenzae, biotype III.
An elderly woman had an abrupt onset of symptoms consistent with bacterial meningitis without an obvious source of infection. The organism, isolated from the blood and CSF, was a nonserotypeableExpand
Observer agreement for small bowel ultrasound in Crohn’s disease: results from the METRIC trial
TLDR
There is substantial practitioner agreement for small bowel disease presence in newly diagnosed and relapsing CD patients, supporting wider dissemination of enteric US. Expand
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