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Ultrastructural alterations in rat and cat retina and pigment epithelium induced by chloroquine
TLDR
In experiments on cats, after a single intravitreous chloroquine injection destruction of the photoreceptors, similar to that observed in rats, was found 2 weeks after the injection, suggesting the protective effect of melanin on the process of chlorquine retinopathy. Expand
Nature of the main contaminant in the anti malaria drug primaquine diphosphate: a qualitative isomer analysis.
TLDR
It is suggested that minor amount of other related substances can contribute more to the toxicity of the drug primaquine diphosphate than the positional isomer quinocide. Expand
[Dirofilariasis in the Moscow Region, a low disease transmission risk area].
TLDR
The spread of canine and human dirofilariasis was first studied in the Moscow Region, a low disease transmission risk area, with the former being preponderant in 31 districts with the imported cases being predominant. Expand
A study of the mechanisms of chloroquine retinopathy. II. Chloroquine effect on protein synthesis of retina.
TLDR
It is shown that chloroquine inhibits rhodopsin synthesis and the renewal of rod outer segment membranes. Expand
A study of the mechanisms of chloroquine retinopathy. I. Chloroquine effect on lipid peroxidation of retina.
TLDR
The influence of chloroquine on lipid peroxidation in rat and rabbit retinas has been studied and it is found that the drug has an inhibitory action on induced lipidperoxidation. Expand
GEOGRAPHIC REGULARITIES IN MICROBE POPULATION (HETEROTROPH) DISTRIBUTION IN THE WORLD OCEAN
The geography of plants and animals has been studied extensively, whereas that of microorganisms has until recently received little attention. It was only within the last decade or so that data onExpand
[The epizootic situation in regions of the North in Russia and the risk of human infection with biohelminthiases].
Mechanisms of retinal damage in chloroquine retinopathy
TLDR
Comparative electron microscopic, electrophysiological and biochemical studies of chloroquine effect on lipid peroxidation both in vitro and in vivo substantiate the idea that LPO is not the primary mechanism in chloroquin retinopathy. Expand
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