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Racemization test in peptide synthesis
  • 47
Studies on Separation of Amino Acids and Related Compounds. V. A Racemization Test in Peptide Synthesis by the Use of an Amino Acid Analyzer
Several tripeptides, H-Gly-DL-Ala-B-OH, in which B residues are DL-alanine, L-valine, L-leucine, L-phenyl-alanine, L-proline, and L-serine have been synthesized and the separation of eachExpand
  • 31
Comparison of Oxidation Products from DNA Components by γ-Irradiation and Fenton-Type Reactions
The four 2'-deoxyribonucleosides were gamma-irradiated or were aerobically treated with Fenton-type-reagents, Fe(II)-EDTA or a renal carcinogen Fe(II)-nitrilotriacetic acid (NTA) under the neutralExpand
  • 66
Copolymers of adenylic and 2-aminoadenylic acids. Effect of progressive changes in hydrogen bonding and stacking on interaction with poly(uridylic acid).
Random copolymers of adenylic acid and 2-aminoadenylic acid form both double and triple helices with poly(uridylic acid) [poly(U)]. Transition temperatures of two-stranded helices increase with 2NH2AExpand
  • 26
Genotoxicity of ribo- and deoxyribonucleosides of 8-hydroxyguanine, 5-hydroxycytosine, and 2-hydroxyadenine: induction of SCE in human lymphocytes and mutagenicity in Salmonella typhimurium TA 100.
The induction of SCE by ribo- and deoxyribonucleosides of 8-hydroxyguanine, 5-hydroxycytosine, and 2-hydroxyadenine was tested using human peripheral blood lymphocytes. All of these compounds causedExpand
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Synthesis and Properties of 2′4′- and 3′-5′-Linked Ribodinucleoside Monophosphates Containing 2-Aminoadenosine and Uridine
Abstract Self complementary diribonucleoside monophosphates containing 2-aminoadenosine (n2A) and uridine (U) residues, (2′-5′) n2ApU (1), (3′-5′) n2ApU (2), (2′-5′) Upn2A (3) and (3′-5′) Upn2A (4),Expand
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The effects of various GTP analogues on microtubule assembly.
We synthesized 27 GTP analogues with modification or substitution at positions C2, C6, C8 and ribose moiety to investigate their effect on microtubule (Mt) assembly. It was found that C2 and C6 areExpand
  • 14
Induction of metallothionein synthesis in transplanted murine tumors by X irradiation.
Although recent studies have shown that radiation can induce metallothionein (MT) synthesis in normal tissues, the induction of tumor MT synthesis by irradiation has not been reported. We examinedExpand
  • 16
Synthesis and Properties of 2,6-Diamino-8,2'-anhydro-8-mercapto-9-β-D-arabinofuranosylpurine
2, 6-Diamino-9-β-D-ribofuranosylpurine (I) was brominated with saturated bromine-water to the 8-bromo compound (II), which was tosylated at the 2'-hydroxygroup via the 2', 3'-O-dibutylstannyleneExpand
  • 13
Syntheses of 2-acylaminoacetamidine and 3-acylaminopropionamidine derivatives.
For the purpose to examine as to their antiviral activities, 2-acylaminoacetamidine (II) and 3-acylaminopropionamidine hydrochlorides (III) were synthesized from the corresponding nitriles via ethylExpand
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