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Power failure: why small sample size undermines the reliability of neuroscience
A study with low statistical power has a reduced chance of detecting a true effect, but it is less well appreciated that low power also reduces the likelihood that a statistically significant resultExpand
Redefine statistical significance
We propose to change the default P-value threshold for statistical significance from 0.05 to 0.005 for claims of new discoveries.
Estimating the reproducibility of psychological science
Empirically analyzing empirical evidence One of the central goals in any scientific endeavor is to understand causality. Experiments that seek to demonstrate a cause/effect relation most oftenExpand
A manifesto for reproducible science
TLDR
We propose a set of measures to optimize key elements of the scientific process: methods, reporting and dissemination, reproducibility, evaluation and incentives. Expand
Delayed reward discounting and addictive behavior: a meta-analysis
RationaleDelayed reward discounting (DRD) is a behavioral economic index of impulsivity and numerous studies have examined DRD in relation to addictive behavior. To synthesize the findings across theExpand
Scanning the horizon: towards transparent and reproducible neuroimaging research
Functional neuroimaging techniques have transformed our ability to probe the neurobiological basis of behaviour and are increasingly being applied by the wider neuroscience community. However,Expand
Serotonin Transporter (5-HTTLPR) Genotype and Amygdala Activation: A Meta-Analysis
BACKGROUND We evaluated the magnitude of the reported associations between amygdala activation and the serotonin transporter gene linked polymorphic region (5-HTTLPR) and the likely effect size ofExpand
Evidence-based guidelines for treating bipolar disorder: Revised third edition recommendations from the British Association for Psychopharmacology
The British Association for Psychopharmacology guidelines specify the scope and targets of treatment for bipolar disorder. The third version is based explicitly on the available evidence andExpand
Interventions for smoking cessation in hospitalised patients.
BACKGROUND An admission to hospital provides an opportunity to help people stop smoking. Individuals may be more open to help at a time of perceived vulnerability, and may find it easier to quit inExpand
Structural neuroimaging studies in major depressive disorder. Meta-analysis and comparison with bipolar disorder.
CONTEXT Although differences in clinical characteristics exist between major depressive disorder (MDD) and bipolar disorder (BD), consistent structural brain abnormalities that distinguish theExpand
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