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Neuroprotective effects of diazepam, carbamazepine, phenytoin and ketamine after pilocarpine-induced status epilepticus.
TLDR
The data point to significant neuroprotective effects of repeated administration of diazepam against status epilepticus-induced cell damage and cognitive disturbances.
Inhibition of acute nociceptive responses in rats after i.c.v. injection of Thr6‐bradykinin, isolated from the venom of the social wasp, Polybia occidentalis
In this work, a neuroactive peptide from the venom of the neotropical wasp Polybia occidentalis was isolated and its anti‐nociceptive effects were characterized in well‐established pain induction
Venom gland transcriptome analyses of two freshwater stingrays (Myliobatiformes: Potamotrygonidae) from Brazil
TLDR
This study elucidated the transcriptomic profile of the venom glands from two different freshwater stingray species that are endemic to the Paraná-Paraguay basin in Brazil, Potamotrygon amandae and Potamotsrygon falkneri and built three-dimensional homology models based on several venom transcripts identified.
Pharmacological Alternatives for the Treatment of Neurodegenerative Disorders: Wasp and Bee Venoms and Their Components as New Neuroactive Tools
TLDR
The present study reviews the current understanding of the mechanisms of action and future prospects regarding the use of new drugs derived from wasp and bee venom in the treatment of major neurodegenerative disorders, including Alzheimer’s Disease, Parkinson's Disease, Epilepsy, Multiple Sclerosis and Amyotrophic Lateral Sclerosis.
Dectin-1 is required for miR155 upregulation in murine macrophages in response to Candida albicans
TLDR
The data suggest that PRR-mediating signaling events are key drivers of miRNA-mediated gene regulation during fungal pathogenesis, and suggest that the C-Type lectin receptor Dectin-1 is a major PRR that orchestrates miR155 upregulation in a Syk-dependent manner.
Arthropod venoms: A vast arsenal of insecticidal neuropeptides
TLDR
This review focuses on invertebrate‐specific peptide neurotoxins that have been isolated from the venom of spiders, scorpions, centipedes, ants, and wasps, discussing their potential in pest control and as invaluable tools in neuropharmacology.
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