Author pages are created from data sourced from our academic publisher partnerships and public sources.
Hypoxia inducible factor activates the transforming growth factor-alpha/epidermal growth factor receptor growth stimulatory pathway in VHL(-/-) renal cell carcinoma cells.
Bi-allelic-inactivating mutations of the VHL tumor suppressor gene are found in the majority of clear cell renal cell carcinomas (VHL(-/-) RCC). VHL(-/-) RCC cells overproduce hypoxia-inducible genes… Expand
Silencing of epidermal growth factor receptor suppresses hypoxia-inducible factor-2-driven VHL-/- renal cancer.
- K. Smith, L. Gunaratnam, M. Morley, A. Franovic, Karim Mekhail, S. Lee
- Biology, Medicine
- Cancer research
- 15 June 2005
Inactivating mutations in the von Hippel-Lindau (VHL) tumor suppressor gene are associated with clear cell renal cell carcinoma (VHL-/- RCC), the most frequent malignancy of the human kidney. The VHL… Expand
Activation of the Integrated Stress Response Regulates Lovastatin-induced Apoptosis*
- N. Niknejad, M. Morley, J. Dimitroulakos
- Biology, Medicine
- Journal of Biological Chemistry
- 12 October 2007
Lovastatin, a potent inhibitor of mevalonate synthesis, can readily induce apoptosis in a subset of human tumor types including head and neck squamous cell carcinomas (HNSCC). We recently identified… Expand
Hypoxia Inducible Factor Activates the Transforming Growth Factor-α/Epidermal Growth Factor Receptor Growth Stimulatory Pathway in VHL-/- Renal Cell Carcinoma Cells*
Bi-allelic-inactivating mutations of the VHL tumor suppressor gene are found in the majority of clear cell renal cell carcinomas (VHL-/- RCC). VHL-/- RCC cells overproduce hypoxia-inducible genes as… Expand
Methodology: U.S. News & World Report Best Hospitals 2013-14
Economic burden of respiratory infections in an employed population.
CONTEXT While respiratory infections are a leading cause of morbidity, there is little information on the costs of medically treating these conditions, or on their workplace impact. OBJECTIVE The… Expand
Post-Acute Care Payment Reform Demonstration: Final Report Volume 1 of 4
PKC inhibition increases gap junction intercellular communication and cell adhesion in human neuroblastoma
Gap junction intercellular communication and cell–cell adhesion are essential for maintaining a normal cellular phenotype, including the control of growth and proliferation. Loss of either cell–cell… Expand
A preliminary look at readmission and mortality among chronically critically ill and other medically complex Medicare patients
ABSTRACT Chronically critically ill and other medically complex patients (CCI/MC-Ps) are those who are hospitalized with long-term intensive care needs and require extended periods of hospital-level… Expand
Measurement, monitoring, and evaluation of state demonstrations to integrate care for dual eligible individuals-Aggregate evaluation plan version 3.0