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Selective transport of alpha-mannosidase by autophagic pathways: identification of a novel receptor, Atg34p.
It is shown that Atg34p (Yol083wp), a homolog of Atg19p, is a receptor for Ams1p transport during autophagy and the interaction of At g34p with Atg8p is crucial for the Ams 1 complex to be enclosed by autophagosomes. Expand
Selective autophagy regulates insertional mutagenesis by the Ty1 retrotransposon in Saccharomyces cerevisiae.
This work shows that selective autophagy downregulates Ty1 transposition by eliminating Ty1 VLPs from the cytoplasm under nutrient-limited conditions, and proposes that selectiveAutophagy safeguards genome integrity against excessive insertional mutagenesis caused during nutrient starvation by transposable elements in eukaryotic cells. Expand
Crystal structure of tripartite-type ABC transporter MacB from Acinetobacter baumannii
The crystal structure of MacB, an ABC transporter in pathogenic microorganisms with unique structural features, is presented at 3.4-Å resolution and compared with other known ABC transporter structures. Expand
Revolver is a New Class of Transposon-like Gene Composing the Triticeae Genome
DNA blot analysis of Triticeae plants shows that Revolver has existed since the diploid progenitor of wheat, and has been amplified or lost in several species during the evolution of the TritICEae. Expand
Proteomic Profiling of Autophagosome Cargo in Saccharomyces cerevisiae
A method for monitoring intact autophagosomes ex vivo by detecting the fluorescence of GFP-fused aminopeptidase I, the best-characterized selective cargo of autophagy in Saccharomyces cerevisiae is developed. Expand
Characterization of Coelomocytes of the Ascidian Halocynthia roretzi Based on Phase-contrast, Time-lapse Video and Scanning Electron Microscopic Observations
Seven types and one sub-type of cells were distinguished with respect to their morphology and behavior of the solitary ascidian Halocynthia roretzi and these cell types are discussed in relation to those appearing in the literature. Expand
Selective Transport of α-Mannosidase by Autophagic Pathways
In Saccharomyces cerevisiae, aminopeptidase I (Ape1p) and α-mannosidase (Ams1p) are known cargoes of selective autophagy. Atg19p has been identified as an Ape1p receptor and targets Ape1p to theExpand
Cilostazol inhibits interleukin‐1‐induced ADAM17 expression through cAMP independent signaling in vascular smooth muscle cells
It is clearly demonstrated that IL‐1 induces ADAM17 expression through ERK/NF‐κB activation in VSMCs and the inhibitory effects of cilostazol onIL‐1‐induced ADam17 expression may be independent of the cAMP signaling pathway in VS MC. Expand
Surface ultrastructure of Heterophyes heterophyes (Trematoda: Heterophyidae) collected from a man
Surface ultrastructur e of Heterophyes heterophyes recovered from a man by treatment with praziquantel is reported, and rodlets were seen to be composed of 3 to 6 spines in a row appearing as "cockscomb". Expand
In Vitro Reactions of Coelomocytes against Sheep Red Blood Cells in the Solitary Ascidian Halocynthia roretzi
Abstract Coelomocytes (blood cells) of the solitary ascidian Halocynthia roretzi were placed in culture to which sheep red blood cells (SRBCs) were introduced. Their reactions against SRBCs wereExpand