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The effect of deleterious mutations on neutral molecular variation.
TLDR
Observed reductions in molecular variation in low recombination genomic regions of sufficiently large size, for instance in the centromere-proximal regions of Drosophila autosomes or in highly selfing plant populations, may be partly due to background selection against deleterious mutations.
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Pollen limitation of plant reproduction: Ecological and evolutionary causes and consequences
TLDR
A change in approach is needed to determine whether pollen limitation reflects random fluctuations around a pollen–resource equilibrium, an adaptation to stochastic pollination environments, or a chronic syndrome caused by an environmental perturbation.
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INBREEDING DEPRESSION, GENETIC LOAD, AND THE EVOLUTION OF OUTCROSSING RATES IN A MULTILOCUS SYSTEM WITH NO LINKAGE
We studied deterministic models of multilocus systems subject to mutation–selection balance with all loci unlinked, and with multiplicative interactions of the loci affecting fitness, in partially…
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Genetic loads and estimates of mutation rates in highly inbred plant populations
TLDR
The inbreeding depression expected in completely inbred populations is derived and used to estimate mutation rates per genome for some plant species.
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The pattern of neutral molecular variation under the background selection model.
TLDR
It is decided whether background selection is sufficient to explain the observed extent of reduction in diversity in regions of restricted recombination, and the power of several tests for the departure from neutral expectation of the frequency spectra of alleles in samples from randomly mating populations are examined.
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Mutation accumulation in finite outbreeding and inbreeding populations
TLDR
The effects of breeding system and rate of recombination on the rate of molecular evolution by the fixation of slightly deleterious alleles are discussed and the effects of differences in the selection parameters (strength of selection, dominance coefficient), of multiplicative versus synergistic selection, and of different amounts of inbreeding are investigated.
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Transposable element number in mixed mating populations.
  • M. Morgan
  • Biology
    Genetical research
  • 1 June 2001
TLDR
Computer simulation and analytic approximations of simplified element dynamics (transposition balanced by selective elimination) in partially self-fertilizing populations, using Ty1-copia elements for biological inspiration are developed.
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EVOLUTION OF A SMALL-MUSCLE POLYMORPHISM IN LINES OF HOUSE MICE SELECTED FOR HIGH ACTIVITY LEVELS
TLDR
It is hypothesized that the small muscles possess functional characteristics and/or that the underlying allele causes pleiotropic effects that facilitate high levels of wheel running, and that multiple genetic “solutions” are possible in response to selection for high activity levels.
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Multilocus models of inbreeding depression with synergistic selection and partial self-fertilization
TLDR
An approximate expression for the inbreeding depression in completely selfing populations is derived, which depends only on the mutation rate and the dominance coefficient and can therefore be used to obtain estimates of the mutations rate to mildly deleterious alleles for plant species.
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Asymmetrical introgression between two Morus species (M. alba, M. rubra) that differ in abundance
TLDR
The results suggest that introgression is bidirectional but asymmetrical and is related, in part, to the relative frequency of parental taxa.
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