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Functional Significance of Collaterals During Ameroid‐induced Coronary Stenosis in Conscious Dogs: Interrelationships Among Regional Shortening, Regional Flow and Grade of Coronary Stenosis
It is confirmed that the development of collateral vessels reduces regional ischemia and hypokinesia induced during abrupt coronary occlusion in a canine model, as estimated from regional shortening rate and the appearance of angiographically opacified collaterals. Expand
A newly developed X-ray transparent ameroid constrictor for study on progression of gradual coronary stenosis
Coronary cineangiography was performed 10, 20 and 30 days after the implantation of the modified ameroid constrictor on the left circumflex coronary artery (LCX), which could prove the progressive coronary stenosis of 57, 78 and 88% on the respective days. Expand
Effects of 2-nicotinamidethyl nitrate (SG-75) and/or nitroglycerin on systemic hemodynamics and coronary blood flow in conscious dogs.
- M. Mizukami, H. Tomoike, T. Inouh, K. Watanabe, Y. Kikuchi, M. Nakamura
- Chemistry, Medicine
The results suggest that the reflex increase in heart rate elicited by pressure drop after SG-75 did not influence the envelope of coronary flow increase such as observed upon NG administration. Expand
Negative inotropic effects of disopyramide on guinea‐pig papillary muscles
The results suggest that disopyramide at high concentrations inhibits Ca influx through slow Ca2+ channels and at low concentrations, it reduces the contraction increased through the Na+‐Ca2+ exchange mechanism. Expand
Chronic instrumentation and its lack of effect on the hemodynamics and regional myocardial blood flow of conscious dogs.
- T. Inou, H. Tomoike, K. Watanabe, M. Mizukami, Y. Kikuchi, M. Nakamura
- Japanese heart journal
- 1 March 1985
A stable hemodynamic state was recorded after the 11th day following surgical manipulation and the implantation of sensors and catheters did not affect the level of regional myocardial blood flow or its distribution at rest. Expand
Experimental myocardial infarction: effects of a lipid peroxide, 13-hydroperoxy linoleic acid on coronary circulation in rats.
It was clearly found that 13-hydroperoxy linoleic acid caused the various endothelial injuries and thrombus formation leading to coronary arterial occlusion and lipid peroxide may play an important role in the pathogenesis of vascular diseases especially in coronary vascular bed. Expand
[The effects of short and long duration of hypothyroidism on prolactin secretion in rats].
- M. Mizukami, S. Kishida, M. Hirai, E. Ooya, T. Nakai, S. Miyabo
- Nihon Naibunpi Gakkai zasshi
- 20 December 1993
A modulatory role for thyroid status is supported in regulating the concentration of DA in the pituitary and the hypothalamus, and consequently on PRL secretion by the Pituitary, in rats induced with experimentally induced hypothyroid state. Expand
Development and application of a radioimmunoassay for 2-hydroxyestriol.
- Y. Fujii, M. Teranishi, +5 authors S. Miyabo
- Chemistry, Medicine
- Chemical & pharmaceutical bulletin
- 25 March 1986
A radioimmunoassay method for the quantitative determination of plasma 2-hydroxyestriol has been developed and it showed high affinity and specificity with low cross-reactivities to structurally related estrogens. Expand
Preparation and antigenic properties of 2-hydroxyestriol-bovine serum albumin conjugate.
Effects of AVS (1,2-bis(nicotinamido)propane) on platelet function and vascular endothelium.
Results clearly show that 1,2-bis(nicotinamido)propane (AVS) may be a new potent anti-vascular damaging agent with both endothelium stabilizing and PGI2 enhancing activities. Expand