• Publications
  • Influence
Prevalence of COPD in Spain: impact of undiagnosed COPD on quality of life and daily life activities
Aims: This study aimed to determine the prevalence of chronic obstructive pulmonary disease (COPD) in Spain and identify the level of undiagnosed disease and its impact on health-related quality ofExpand
  • 596
  • 30
  • Open Access
Health outcomes following treatment for six months with once daily tiotropium compared with twice daily salmeterol in patients with COPD.
BACKGROUND A study was undertaken to record exacerbations and health resource use in patients with COPD during 6 months of treatment with tiotropium, salmeterol, or matching placebos. METHODSExpand
  • 307
  • 24
  • Open Access
Outcomes for COPD pharmacological trials: from lung function to biomarkers
The American Thoracic Society/European Respiratory Society jointly created a Task Force on “Outcomes for COPD pharmacological trials: from lung function to biomarkers” to inform the chronicExpand
  • 429
  • 21
Epidemiology and costs of chronic obstructive pulmonary disease
SERIES “THE GLOBAL BURDEN OF CHRONIC OBSTRUCTIVE PULMONARY DISEASE” Edited by K.F. Rabe and J.B. Soriano Number 1 in this Series Chronic obstructive pulmonary disease (COPD) is a leadingExpand
  • 651
  • 18
Chronic obstructive pulmonary disease
Summary Chronic obstructive pulmonary disease (COPD) is characterised by progressive airflow obstruction that is only partly reversible, inflammation in the airways, and systemic effects orExpand
  • 381
  • 17
  • Open Access
Health outcomes following treatment for 6 months with once daily tiotropium compared with twice daily salmeterol in patients with COPD
We wish to clarify issues raised by your recent letter regarding the abovementioned paper published in May 2003 in Thorax (2003; 58 :399–404). Our intention was to notify the editors and to referenceExpand
  • 405
  • 16
  • Open Access
Symptom variability in patients with severe COPD: a pan-European cross-sectional study
In between exacerbations, chronic obstructive pulmonary disease (COPD) is usually regarded as a stable condition, but there is increasing recognition of variability in this state. ThisExpand
  • 287
  • 15
Effect of exacerbations on quality of life in patients with chronic obstructive pulmonary disease: a 2 year follow up study
Background: A study was undertaken to evaluate exacerbations and their impact on the health related quality of life (HRQL) of patients with chronic obstructive pulmonary disease (COPD). Methods: A 2Expand
  • 483
  • 13
  • Open Access
Relationship between bacterial flora in sputum and functional impairment in patients with acute exacerbations of COPD. Study Group of Bacterial Infection in COPD.
STUDY OBJECTIVES To investigate the possible relationship between functional respiratory impairment measured by FEV1 and isolation of diverse pathogens in the sputum of patients with exacerbations ofExpand
  • 426
  • 11
Factors Associated with Increased Risk of Exacerbation and Hospital Admission in a Cohort of Ambulatory COPD Patients: A Multiple Logistic Regression Analysis
Background and Objective: The aim of this study was to develop and validate two models to estimate the probabilities of frequent exacerbations (more than 1 per year) and admissions for chronicExpand
  • 294
  • 11
  • Open Access