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Genetic studies of body mass index yield new insights for obesity biology
Obesity is heritable and predisposes to many diseases. To understand the genetic basis of obesity better, here we conduct a genome-wide association study and Metabochip meta-analysis of body massExpand
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Defining the role of common variation in the genomic and biological architecture of adult human height
Using genome-wide data from 253,288 individuals, we identified 697 variants at genome-wide significance that together explained one-fifth of the heritability for adult height. By testing differentExpand
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Maternal age and fetal loss: population based register linkage study
Abstract Objective: To estimate the association between maternal age and fetal death (spontaneous abortion, ectopic pregnancy, stillbirth), taking into account a woman's reproductive history. Design:Expand
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Genome partitioning of genetic variation for complex traits using common SNPs
We estimate and partition genetic variation for height, body mass index (BMI), von Willebrand factor and QT interval (QTi) using 586,898 SNPs genotyped on 11,586 unrelated individuals. We estimateExpand
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The Danish National Birth Cohort - its background, structure and aim
Background: It is well known that the time from conception to early childhood has importance for health conditions that reach into later stages of life. Recent research supports this view, andExpand
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A genome-wide association study of cleft lip with and without cleft palate identifies risk variants near MAFB and ABCA4
Case-parent trios were used in a genome-wide association study of cleft lip with and without cleft palate. SNPs near two genes not previously associated with cleft lip with and without cleft palateExpand
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Autoimmune and chronic inflammatory disorders and risk of non-Hodgkin lymphoma by subtype.
BACKGROUND Some autoimmune and chronic inflammatory disorders are associated with increased risks of non-Hodgkin lymphoma (NHL). Because different NHL subtypes develop at different stages ofExpand
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A population-based study of measles, mumps, and rubella vaccination and autism.
BACKGROUND It has been suggested that vaccination against measles, mumps, and rubella (MMR) is a cause of autism. METHODS We conducted a retrospective cohort study of all children born in DenmarkExpand
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Effects of family history and place and season of birth on the risk of schizophrenia.
BACKGROUND Although a family history of schizophrenia is the best-established risk factor for schizophrenia, environmental factors such as the place and season of birth may also be important. Expand
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Recurrence of Congenital Heart Defects in Families
Background— Knowledge of the familial contribution to congenital heart diseases (CHD) on an individual and population level is sparse. We estimated an individual’s risk of CHD given a family historyExpand
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