M. McHugh

Publications15
h-index7
Citations3,572
Highly Influential Citations165
Claim Author Page
Author pages are created from data sourced from our academic publisher partnerships and public sources.

Recommended Authors

  • J. Jez
  • 309 Publications • 8,790 Citations
  • W. Witola
  • 66 Publications • 1,298 Citations
  • A. Robertson
  • 89 Publications • 2,257 Citations
  • S. Lee
  • 62 Publications • 671 Citations
  • Publications
  • Influence
BAY 43-9006 Exhibits Broad Spectrum Oral Antitumor Activity and Targets the RAF/MEK/ERK Pathway and Receptor Tyrosine Kinases Involved in Tumor Progression and Angiogenesis
The RAS/RAF signaling pathway is an important mediator of tumor cell proliferation and angiogenesis. The novel bi-aryl urea BAY 43-9006 is a potent inhibitor of Raf-1, a member of the RAF/MEK/ERK… Expand
HGF/c-Met axis drives cancer aggressiveness in the neo-adjuvant setting of ovarian cancer
Ovarian cancer is the most lethal gynecologic malignancy. Recently, NACT (Neo Adjuvant Chemotherapy) has been tested as alternative approach for the management of ovarian cancer patients. A… Expand
HGF/c-Met axis drives cancer aggressiveness in the neo-adjuvant setting of ovarian cancer
Ovarian cancer is the most lethal gynecologic malignancy. Recently, NACT (Neo Adjuvant Chemotherapy) has been tested as alternative approach for the management of ovarian cancer patients. A… Expand
Knockdown of phosphoethanolamine transmethylation enzymes decreases viability of Haemonchus contortus.
The phosphobase methylation pathway, in which phosphoethanolamine N-methyltransferases (PMTs) successively catalyze the methylation of phosphoethanolamine to phosphocholine, is essential in the… Expand
Silencing of GRA10 protein expression inhibits Toxoplasma gondii intracellular growth and development.
Toxoplasma gondii dense granule proteins (GRAs) are secreted abundantly in both the tachyzoite and bradyzoite stages of the parasite and are known to localize to various compartments of the… Expand
Herpes Virus MicroRNA Expression and Significance in Serous Ovarian Cancer
Serous ovarian cancer (SEOC) is the deadliest gynecologic malignancy. MicroRNAs (miRNAs) are a class of small noncoding RNAs which regulate gene expression and protein translation. MiRNAs are also… Expand
In vitro anthelmintic efficacy of inhibitors of phosphoethanolamine Methyltransferases in Haemonchus contortus
The essential phosphobase methylation pathway for synthesis of phosphocholine is unique to nematodes, protozoa and plants, and thus an attractive antiparasitic molecular target. Herein, we screened… Expand
Integrated Multidimensional Analysis Is Required for Accurate Prognostic Biomarkers in Colorectal Cancer
CRC cancer is one of the deadliest diseases in Western countries. In order to develop prognostic biomarkers for CRC (colorectal cancer) aggressiveness, we analyzed retrospectively 267 CRC patients… Expand
HGF/c-Met axis drives cancer aggressiveness in the neoadjuvant setting of ovarian cancer
139 BAY 57-9352: an inhibitor of VEGFR-2 and PDGFR receptor tyrosine kinases that demonstrates anti-angiogenic activity in vitro and in vivo
...
1
2
...