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- Publications
- Influence
Etiologic connections among substance dependence, antisocial behavior, and personality: modeling the externalizing spectrum.
- R. Krueger, B. Hicks, C. Patrick, S. R. Carlson, W. Iacono, M. McGue
- Medicine, Psychology
- Journal of abnormal psychology
- 2002
A hierarchical biometric model is presented of the origins of comorbidity among substance dependence, antisocial behavior, and a disinhibited personality style. The model posits a spectrum of… Expand
Next-generation genotype imputation service and methods
- S. Das, Lukas Forer, +18 authors C. Fuchsberger
- Biology, Medicine
- Nature Genetics
- 1 October 2016
Genotype imputation is a key component of genetic association studies, where it increases power, facilitates meta-analysis, and aids interpretation of signals. Genotype imputation is computationally… Expand
A reference panel of 64,976 haplotypes for genotype imputation
- S. McCarthy, S. Das, +106 authors R. Durbin
- Biology, Medicine
- Nature Genetics
- 22 August 2016
We describe a reference panel of 64,976 human haplotypes at 39,235,157 SNPs constructed using whole-genome sequence data from 20 studies of predominantly European ancestry. Using this resource leads… Expand
Genome-wide association study identifies 74 loci associated with educational attainment
- A. Okbay, J. Beauchamp, +252 authors D. Benjamin
- Biology, Medicine
- Nature
- 31 March 2016
Educational attainment is strongly influenced by social and other environmental factors, but genetic factors are estimated to account for at least 20% of the variation across individuals. Here we… Expand
GWAS of 126,559 Individuals Identifies Genetic Variants Associated with Educational Attainment
- C. A. Rietveld, Sarah E Medland, +200 authors P. Koellinger
- Biology, Medicine
- Science
- 21 June 2013
Genetic College Many genomic elements in humans are associated with behavior, including educational attainment. In a genome-wide association study including more than 100,000 samples, Rietveld et al.… Expand
Genetic variants associated with subjective well-being, depressive symptoms and neuroticism identified through genome-wide analyses
- A. Okbay, B. Baselmans, +184 authors D. Cesarini
- Biology, Medicine
- Nature Genetics
- 18 April 2016
Very few genetic variants have been associated with depression and neuroticism, likely because of limitations on sample size in previous studies. Subjective well-being, a phenotype that is… Expand
Prospective effects of attention-deficit/hyperactivity disorder, conduct disorder, and sex on adolescent substance use and abuse.
CONTEXT
Attention-deficit/hyperactivity disorder (ADHD), an early manifestation of externalizing behavior, may identify children at high risk for later substance abuse. However, the ADHD-substance… Expand
Familial studies of intelligence: a review.
- T. Bouchard, M. McGue
- Psychology, Medicine
- Science
- 29 May 1981
A summary of 111 studies identified in a survey of the world literature on familial resemblances in measured intelligence reveals a profile of average correlations consistent with a polygenic mode of… Expand
Predictors of Mortality in 2,249 Nonagenarians—The Danish 1905‐Cohort Survey
- H. Nybo, H. C. Petersen, +5 authors K. Christensen
- Medicine
- Journal of the American Geriatrics Society
- 1 October 2003
Objectives: To elucidate whether well‐known predictions of mortality are reduced or even reversed, or whether mortality is a stochastic process in the oldest old.
Sources of human psychological differences: the Minnesota Study of Twins Reared Apart.
- T. Bouchard, D. Lykken, M. McGue, N. Segal, A. Tellegen
- Medicine, Psychology
- Science
- 12 October 1990
Since 1979, a continuing study of monozygotic and dizygotic twins, separated in infancy and reared apart, has subjected more than 100 sets of reared-apart twins or triplets to a week of intensive… Expand