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Early real-world effectiveness of ustekinumab for Crohn’s disease
Objective To understand the effectiveness of ustekinumab in treating Crohn’s disease (CD) in a UK real-world setting. Design Retrospective cohort study using prospectively maintained clinicalExpand
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OTU-26 Data driven service evaluation of an IBD helpline
Introduction We present a data driven service evaluation of the use of an Inflammatory Bowel Disease (IBD) telephone helpline service at a single UK IBD centre (UHS). We demonstrate how suchExpand
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High incidence of glucocorticoid-induced hyperglycaemia in inflammatory bowel disease: metabolic and clinical predictors identified by machine learning
Background Glucocorticosteroids (GC) are long-established, widely used agents for induction of remission in inflammatory bowel disease (IBD). Hyperglycaemia is a known complication of GC treatmentExpand
OTH-03 Impact of direct access IBD physician delivered sigmoidoscopy from acute IBD flare line call service
Introduction Inflammatory bowel disease (IBD) patients calling our specialist nurse led IBD flare line with worsening symptoms were traditionally seen in outpatient clinics before being referred forExpand
PTH-081 Ustekinumab treatment strategies in refractory Crohn’s Disease: Real-world effectiveness data from a UK IBD centre
Introduction Ustekinumab (UST) is a human IgG1 kappa mAb to the shared p40 subunit of IL-12 and IL-23 which are involved in TH1 and TH17 mediated pathways of Crohn’s disease (CD) pathogenesis. NICEExpand
Evolution of an inflammatory bowel disease helpline and implications for service design and development
Inflammatory bowel disease (IBD) clinical nurse specialists deliver a service that is highly valued by patients. Access to a specialist nurse-led IBD helpline forms part of the UK IBD consensus sta...
High incidence of glucocorticoid-induced hyperglycaemia in inflammatory bowel disease; metabolic and clinical predictors identified by machine learning
Background Glucocorticosteroids (GC) are long-established, widely used agents for induction of remission in inflammatory bowel disease (IBD). Hyperglycaemia is a known complication of GC treatmentExpand
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The monitoring and incidence of hyperglycaemia in inflammatory bowel disease patients treated with intravenous steroids
To improve detection and establish the frequency of steroid-induced hyperglycaemia among inpatients with a flare of inflammatory bowel disease (IBD) receiving intravenous hydrocortisone by improvingExpand
PTH-105 Hyperglycaemia in steroid treated hospitalised IBD inpatients and its risk factors identified by machine learning
Introduction Glucocorticoids (GC) have been first line treatment for hospitalised IBD patients for over 60 years, despite the introduction of biologic therapy. IBD patients often have systemicExpand