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- Publications
- Influence
Nickel differentially affects NMDA receptor channels in developing cultured rat neurons
- P. Gavazzo, M. Mazzolini, M. Tedesco, C. Marchetti
- Medicine, Biology
- Brain Research
- 17 March 2006
Nickel (Ni(2+)) is a transition metal that exerts multiple and complex effects on N-methyl-d-aspartate (NMDA) channels. In both HEK293 cells and Xenopus laevis oocytes expressing recombinant NMDA… Expand
Lead inhibition of NMDA channels in native and recombinant receptors
- P. Gavazzo, A. Gazzoli, M. Mazzolini, C. Marchetti
- Biology, Medicine
- Neuroreport
- 8 October 2001
NMDA channels are key targets for lead (Pb2+) neurotoxicity and Pb2+-induced inhibition of NMDA current is age- and subunit-dependent. In rat cerebellar granule cells maintained in high KCl, glycine… Expand
Multiple pathways of Pb2+ permeation in rat cerebellar granule neurones
- M. Mazzolini, S. Traverso, C. Marchetti
- Chemistry, Medicine
- Journal of neurochemistry
- 1 October 2001
The pathways of lead (Pb2+) uptake were studied in fura‐2‐loaded cerebellar granule cells from 8‐day‐old rats. In a nominal Ca‐free external bath, Pb2+ (5–50 µm) determined an increase of the… Expand
The Voltage Sensor Of Cnga1 Channels Becomes Functional When The Hydrophobic Bond Between Phe380 And Leu356 Is Impaired
- M. Mazzolini
- Chemistry
- 1 February 2009
The super-family of voltage gated ionic channels comprises usual voltage-dependent Na+, K+ and Ca2+ channels, but also cyclic nucleotide gated (CNG) channels which are not voltage dependent. Voltage… Expand