• Publications
  • Influence
Methuselah Flies: A Case Study in the Evolution of Aging
Creation and Long-Term Evolution of Methuselah Flies Stress Resistance, Physiology, and Aging Reproduction, Nutrition, and Aging Genetics and Molecular Biology of Methuselah Flies Reverse EvolutionExpand
  • 85
  • 5
How Repeatable is Adaptive Evolution? The Role of Geographical Origin and Founder Effects in Laboratory Adaptation
Abstract The importance of contingency versus predictability in evolution has been a long-standing issue, particularly the interaction between genetic background, founder effects, and selection. HereExpand
  • 85
  • 5
  • PDF
Variation in the rate of convergent evolution: adaptation to a laboratory environment in Drosophila subobscura
Adaptation to novel environments is a central issue in evolutionary biology. One important question is the prevalence of convergence when different populations adapt to the same or similarExpand
  • 56
  • 5
  • PDF
Reverse evolution of fitness in Drosophila melanogaster
Abstract The evolution of fitness is central to evolutionary theory, yet few experimental systems allow us to track its evolution in genetically and environmentally relevant contexts. ReverseExpand
  • 53
  • 4
  • PDF
CLINAL PATTERNS OF CHROMOSOMAL INVERSION POLYMORPHISMS IN DROSOPHILA SUBOBSCURA ARE PARTLY ASSOCIATED WITH THERMAL PREFERENCES AND HEAT STRESS RESISTANCE
Latitudinal clines in the frequency of various chromosomal inversions are well documented in Drosophila subobscura. Because these clines are roughly parallel on three continents, they haveExpand
  • 54
  • 3
  • PDF
From nature to the laboratory: the impact of founder effects on adaptation
Most founding events entail a reduction in population size, which in turn leads to genetic drift effects that can deplete alleles. Besides reducing neutral genetic variability, founder effects can inExpand
  • 31
  • 3
  • PDF
SYMMETRY BREAKING IN INTERSPECIFIC DROSOPHILA HYBRIDS IS NOT DUE TO DEVELOPMENTAL NOISE
Abstract Hybrids from crosses of different species have been reported to display decreased developmental stability when compared to their pure species, which is conventionally attributed to aExpand
  • 28
  • 3
  • PDF
HAMILTON'S FORCES OF NATURAL SELECTION AFTER FORTY YEARS
Abstract In 1966, William D. Hamilton published a landmark paper in evolutionary biology: “The Moulding of Senescence by Natural Selection.” It is now apparent that this article is as important asExpand
  • 72
  • 2
  • PDF
Climate change and chromosomal inversions in Drosophila subobscura
In natural populations, the large changes in chromosomal structure occurring through chromosomal inversions show pronounced variations in frequency that often correspond to temporal and spatialExpand
  • 47
  • 2
  • PDF
The Effects of Evolution are Local: Evidence from Experimental Evolution in Drosophila1
Abstract One of the enduring temptations of evolutionary theory is the extrapolation from short-term to long-term, from a few species to all species. Unfortunately, the study of experimentalExpand
  • 45
  • 2
  • PDF
...
1
2
3
4
5
...