Brainstem activation specific to migraine headache
- A. Bahra, M. Matharu, C. Buchel, R. Frackowiak, P. Goadsby
- Medicine, PsychologyThe Lancet
- 31 March 2001
A PET study exploring the laterality of brainstem activation in migraine using glyceryl trinitrate.
- S. Afridi, M. Matharu, P. Goadsby
- Psychology, BiologyBrain : a journal of neurology
- 1 September 2004
Results suggest that lateralization of pain in migraine is due to lateralized brain dysfunction, and the activation persisted after pain was controlled by sumatriptan.
Central neuromodulation in chronic migraine patients with suboccipital stimulators: a PET study.
- M. Matharu, T. Bartsch, N. Ward, Richard S. J. Frackowiak, R. Weiner, P. Goadsby
- Medicine, PsychologyBrain : a journal of neurology
- 2004
The activation pattern in the dorsal rostral pons is highly suggestive of a role for this structure in the pathophysiology of chronic migraine and the localization and persistence of activity during stimulation is exactly consistent with a region activated in episodic migraine, and with the persistence of activation of that area after successful treatment.
Efficacy and safety of galcanezumab for the prevention of episodic migraine: Results of the EVOLVE-2 Phase 3 randomized controlled clinical trial
- V. Skljarevski, M. Matharu, B. Millen, M. Ossipov, Byung-Kun Kim, J. Yang
- Medicine, PsychologyCephalalgia
- 31 May 2018
Galcanezumab 120 or 240 mg given once monthly was efficacious, safe, and well tolerated and both doses were superior to placebo for all key secondary endpoints.
Short-lasting unilateral neuralgiform headache attacks with conjunctival injection and tearing (SUNCT) or cranial autonomic features (SUNA)--a prospective clinical study of SUNCT and SUNA.
- A. Cohen, M. Matharu, P. Goadsby
- MedicineBrain : a journal of neurology
- 1 October 2006
A new set of diagnostic criteria for these syndromes is proposed to better encompass the clinical presentations and which include a wider range of attack length, wider trigeminal pain distribution, cutaneous triggering and lack of refractory period.
The clinical characteristics of headache in patients with pituitary tumours.
- M. Levy, M. Matharu, K. Meeran, M. Powell, P. Goadsby
- Medicine, PsychologyBrain : a journal of neurology
- 1 August 2005
Headache appears to be a significant problem in pituitary disease and is associated with a range of headache phenotypes, likely to be governed by a combination of factors, including tumour activity, relationship to the cavernous sinus and patient predisposition to headache.
Clinical Presentation, Investigation Findings, and Treatment Outcomes of Spontaneous Intracranial Hypotension Syndrome
- L. D’Antona, Melida Andrea Jaime Merchan, M. Matharu
- Medicine, PsychologyJAMA Neurology
- 4 January 2021
This systematic review and meta-analysis provides an objective summary of the available evidence on the clinical presentation, investigations findings, and treatment outcomes for spontaneous…
Subcutaneous octreotide in cluster headache: Randomized placebo‐controlled double‐blind crossover study
- M. Matharu, M. Levy, K. Meeran, P. Goadsby
- Medicine, PsychologyAnnals of Neurology
- 1 October 2004
Subcutaneous octreotide 100μg is effective in the acute treatment of cluster headache when compared with placebo and nonvasconstrictor treatment of acute cluster headache is possible.
Posterior hypothalamic activation in paroxysmal hemicrania
- M. Matharu, A. Cohen, Richard S. J. Frackowiak, P. Goadsby
- Medicine, PsychologyAnnals of Neurology
- 1 March 2006
The purpose of the study was to determine the brain structures active in paroxysmal hemicrania.
Paroxysmal hemicrania: a prospective clinical study of 31 cases.
- E. Cittadini, M. Matharu, P. Goadsby
- MedicineBrain : a journal of neurology
- 1 April 2008
The International Headache Society criteria for paroxysmal hemicrania should be revised to remove specification of attack site, and to include the full range of cranial autonomic features.
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