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Huntington disease: volumetric, diffusion-weighted, and magnetization transfer MR imaging of brain.
PURPOSE To investigate whether diffusion-weighted and magnetization transfer (MT) magnetic resonance (MR) imaging depict regional and/or global brain abnormalities in patients with Huntington diseaseExpand
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Regional Distribution and Clinical Correlates of White Matter Structural Damage in Huntington Disease: A Tract-Based Spatial Statistics Study
BACKGROUND AND PURPOSE: HD entails damage of the WM. Our aim was to explore in vivo the regional volume and microstructure of the brain WM in HD and to correlate such findings with clinical status ofExpand
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Axial diffusivity is increased in the degenerating superior cerebellar peduncles of Friedreich's ataxia
IntroductionDecreased fractional anisotropy (FA) demonstrated by diffusion tensor MR imaging (DTI) in areas of white matter (WM) damage is generally associated with increase of radial diffusivity,Expand
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The Present and the Future of Neuroimaging in Amyotrophic Lateral Sclerosis
SUMMARY: In patients with ALS, conventional MR imaging is frequently noninformative, and its use has been restricted to excluding other conditions that can mimic ALS. Conversely, the extensiveExpand
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Brain white matter tracts degeneration in Friedreich ataxia. An in vivo MRI study using tract-based spatial statistics and voxel-based morphometry
TLDR
Tract-based spatial statistics (TBSS) enables an unbiased whole-brain quantitative analysis of the fractional anisotropy (FA) and mean diffusivity (MD) of the brain WM tracts in vivo. Expand
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Assessment of brain white matter fiber bundle atrophy in patients with Friedreich ataxia.
PURPOSE To investigate in vivo severity and topographic distribution of brain white matter (WM) fiber bundle atrophy in patients with Friedreich ataxia, a condition characterized by an unevenExpand
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Four-Year Results of Low-Dose CT Screening and Nodule Management in the ITALUNG Trial
Introduction: Recruitment and nodule management are critical issues of lung cancer screening with low-dose computed tomography (LDCT). We report subjects’ compliance and results of LDCT screening andExpand
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3-D Segmentation Algorithm of Small Lung Nodules in Spiral CT Images
TLDR
We propose a semiautomatic method for 3-D segmentation of lung nodules in CT images for subsequent volume assessment. Expand
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Automated Segmentation Refinement of Small Lung Nodules in CT Scans by Local Shape Analysis
TLDR
We propose an automated correction method applied to an initial rough segmentation of the lung nodule, based on a local shape analysis of the initial segmentation boundary. Expand
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Chronic obstructive pulmonary disease: thin-section CT measurement of airway wall thickness and lung attenuation.
PURPOSE To prospectively evaluate airway wall thickness and lung attenuation at spirometrically gated thin-section computed tomography (CT) in patients with chronic obstructive pulmonary diseaseExpand
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