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Broad phylogenomic sampling improves resolution of the animal tree of life
TLDR
This data reinforce several previously identified clades that split deeply in the animal tree, unambiguously resolve multiple long-standing issues for which there was strong conflicting support in earlier studies with less data, and provide molecular support for the monophyly of molluscs, a group long recognized by morphologists. Expand
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
TLDR
Two small RNAs regulate the timing of Caenorhabditis elegans development and may control late temporal transitions during development across animal phylogeny. Expand
Assessing the root of bilaterian animals with scalable phylogenomic methods
  • A. Hejnol, M. Obst, +14 authors C. Dunn
  • Biology, Medicine
  • Proceedings of the Royal Society B: Biological…
  • 22 December 2009
TLDR
New sequence data and methods strongly uphold previous suggestions that Acoelomorpha is sister clade to all other bilaterian animals, find diminishing evidence for the placement of the enigmatic Xenoturbella within Deuterostomia, and place Cycliophora with Entoprocta and EctoproCTa. Expand
Sea Anemone Genome Reveals Ancestral Eumetazoan Gene Repertoire and Genomic Organization
TLDR
A comparative analysis of the draft genome of an emerging cnidarian model, the starlet sea anemone Nematostella vectensis, suggests that gene “inventions” along the lineage leading to animals were likely already well integrated with preexisting eukaryotic genes in the eumetazoan progenitor. Expand
The Genome of the Ctenophore Mnemiopsis leidyi and Its Implications for Cell Type Evolution
TLDR
The genome of the ctenophore the warty comb jelly or sea walnut, Mnemiopsis leidyi, is sequenced and it is concluded that c tenophores alone, not sponges or the clade consisting of both ctenphores and cnidarians, are the most basal extant animals. Expand
Unexpected complexity of the Wnt gene family in a sea anemone
TLDR
The isolation of twelve Wnt genes from the sea anemone Nematostella vectensis, a species representing the basal group within cnidarians, indicates distinct roles of Wnts in gastrulation, resulting in serial overlapping expression domains along the primary axis of the planula larva. Expand
Investigating the origins of triploblasty: `mesodermal' gene expression in a diploblastic animal, the sea anemone Nematostella vectensis (phylum, Cnidaria; class, Anthozoa)
TLDR
The developmental expression of seven genes from Nematostella are studied, and the predominantly endodermal expression of these genes reinforces the hypothesis that the mesoderm and endoderm of triploblastic animals could be derived from the endoderman of a diploblastics ancestor. Expand
Origins of Bilateral Symmetry: Hox and Dpp Expression in a Sea Anemone
TLDR
It is shown that Nematostella uses homologous genes to achieve bilateral symmetry: Multiple Hox genes are expressed in a staggered fashion along its primary body axis, and the transforming growth factor–β gene decapentaplegic is expressed in an asymmetric fashion about its secondary body axis. Expand
A WNT of things to come: evolution of Wnt signaling and polarity in cnidarians.
TLDR
What is currently known about Wnt signaling in cnidarians is examined, and what this group of "simple" animals may reveal about the evolution of WNT signaling and polarity is discussed. Expand
Anatomy and development of the nervous system of Nematostella vectensis, an anthozoan cnidarian
TLDR
Early neurons and stem cell populations identified with NvMsi, NvELAV, and NvGCM, indicate that neural differentiation occurs throughout the animal and initiates prior to the conclusion of gastrulation. Expand
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