M. Marley

Publications38
h-index13
Citations575
Highly Influential Citations17
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Infectious causes of embryonic and fetal mortality
TLDR
Bacterial, fungal, protozoan, and viral causes of reproductive dysgenesis in cattle, sheep, goats, pigs, horses, dogs, and cats are summarized to avoid zoonotic infections resulting from reproductive pathogens of animals.
Reproductive and economic impact following controlled introduction of cattle persistently infected with bovine viral diarrhea virus into a naive group of heifers.
TLDR
The active immunity that developed following field exposure to BVDV provided effective reproductive and fetal protection during the breeding season and subsequent gestations, despite continuous exposure to PI animals until approximately midgestation.
Bovine viral diarrhea virus (BVDV) associated with single in vivo-derived and in vitro-produced preimplantation bovine embryos following artificial exposure.
TLDR
Although many embryos were positive for virus, there were limited numbers of copies, thereby posing doubt regarding their potential for contamination following embryo transfer.
Pathogens that cause infertility of bulls or transmission via semen.
TLDR
Adhering to disease control recommendations provided by Certified Semen Services and the World Organization for Animal Health can prevent infectious male infertility and ensure that the risk of pathogen transmission via semen is negligible.
Protective effects against abortion and fetal infection following exposure to bovine viral diarrhea virus and bovine herpesvirus 1 during pregnancy in beef heifers that received two doses of a…
TLDR
Prebreeding administration of a modified-live virus vaccine to heifers resulted in fewer abortions and BVDV-PI offspring and improved growth and increased market value of weaned calves.
Development of a duplex quantitative polymerase chain reaction assay for detection of bovine herpesvirus 1 and bovine viral diarrhea virus in bovine follicular fluid.
TLDR
The duplex qPCR might be used for quality assurance testing to identify these two viruses in cells, fluids and tissues collected from donor animals and used in reproductive technologies.
Efficacy of an antiviral compound to inhibit replication of multiple pestivirus species.
TLDR
DB772 effectively inhibits all pestiviruses studied at concentrations >0.20μM, as cytotoxicity is not evident at these concentrations, this antiviral compound potentially represents an effective preventative or therapeutic for diverse pestIViruses.
Comparison of three commercial vaccines for preventing persistent infection with bovine viral diarrhea virus.
TLDR
Commercial vaccines provided effective fetal protection despite prolonged natural exposure to BVDV, and there is continued need for biosecurity and diagnostic surveillance, in addition to vaccination, to ensure effective BVDVs control.
Antiviral Treatment of Calves Persistently Infected with Bovine Viral Diarrhoea Virus
TLDR
Results demonstrate that DB772 administration is safe and exhibits antiviral properties in PI calves while facilitating the rapid development of viral resistance to this novel therapeutic agent.
Risk and prevention of bovine viral diarrhea virus (BVDV) transmission through embryo production via somatic cell nuclear transfer (SCNT) using oocytes from persistently infected donors.
TLDR
Routine testing of unacceptable (discarded) oocytes could be an effective approach to identify batches that might contain infected oocytes from persistently infected (PI) donors and minimize the risk of BVDV transmission through SCNT embryo production.
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