• Publications
  • Influence
Paradoxical helminthiasis and giardiasis in Cape Town, South Africa: epidemiology and control.
TLDR
Prevalence trends in this old community in Cape Town could indicate infection by swallowing eggs or cysts on food or in water, more than by exposure to polluted soil, and the immune response to intestinal parasites might be a risk factor for HIV/AIDS and TB. Expand
Could control of soil-transmitted helminthic infection influence the HIV/AIDS pandemic.
TLDR
There is an urgent need for parasitologists, epidemiologists, immunologists and virologists to undertake comprehensive, transdisciplinary research on the new dimension created by the HIV/AIDS epidemics in the same impoverished communities and countries where helminthiasis is hyperendemic. Expand
Advantages of using mitochondrial 16S rDNA sequences to classify clinical isolates of Acanthamoeba.
TLDR
The phylogenetic clustering of AK isolates was confirmed and thus is not specific to the nuclear gene, and Rns and rns sequences are both suitable for genotyping of Acanthamoeba. Expand
In vitro sensitivity of southern African reference isolates of Plasmodium falciparum to chloroquine and pyrimethamine.
TLDR
The results confirm the presence of both chloroquine and pyrimethamine resistance in the endemic areas of South Africa and has serious implications for the prophylaxis and treatment of P. falciparum malaria in South Africa. Expand
Anti-Acanthamoeba activity of contact lens solutions
TLDR
Investigation of the effects of contact lens disinfecting solutions on strains of Acanthamoeba from the United Kingdom and southern Africa and to compare the results with those of other researchers found the killing time for cysts of the African and UK isolates studied is similar. Expand
The hypnozoite concept, with particular reference to malaria
  • M. Markus
  • Biology, Medicine
  • Parasitology Research
  • 2010
TLDR
This paper is based on a presentation by the author, as a Life Member of the American Society of Tropical Medicine and Hygiene, to its 59th Annual Meeting in Atlanta, Georgia, USA, 3–7 November 2010, and explains how the name “hypnozoite” is applicable to a latent stage in the life cycle of Plasmodium but to some apparently dormant forms of other kinds of apicomplexan parasites as well. Expand
Efficacy of albendazole against the whipworm trichuris trichiura--a randomised, controlled trial.
TLDR
Albendazole cannot be used in deworming programmes in South Africa because it is a Schedule 4 prescription medicine, and de-scheduling is needed urgently, particularly because of high efficacy against hookworm in KwaZulu-Natal and neighbouring countries. Expand
Malaria: Origin of the Term “Hypnozoite”
  • M. Markus
  • Biology, Medicine
  • Journal of the history of biology
  • 2011
TLDR
The hypnozoite is a dormant forms in the life cycles of certain parasitic protozoa that belong to the Phylum Apicomplexa (Sporozoa) and are best known for their probable association with latency and relapse in human malarial infections caused by Plasmodium ovale and P. vivax. Expand
Recall of intestinal helminthiasis by HIV-infected South Africans and avoidance of possible misinterpretation of egg excretion in worm/HIV co-infection analyses
TLDR
It is postulate that when Ascaris is hyperendemic, analysis of possible consequences of co-infection by HIV cannot be based primarily on excretion vs non-excretion of eggs, and comparisons must be based mainly on disease-related immunological variables. Expand
Late stone-age coprolite reveals evidence of prehistoric parasitism.
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