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Arachidonic Acid-metabolizing Cytochrome P450 Enzymes Are Targets of ω-3 Fatty Acids*
TLDR
It is found that these ω-3 epoxides are highly active as antiarrhythmic agents, suppressing the Ca2+-induced increased rate of spontaneous beating of neonatal rat cardiomyocytes, at low nanomolar concentrations.
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Mouse Cyp4a isoforms: enzymatic properties, gender- and strain-specific expression, and role in renal 20-hydroxyeicosatetraenoic acid formation.
TLDR
Cyp4a12a expression determines the sex- and strain-specific differences in 20-HETE generation and may explain sex and strain differences in the susceptibility to hypertension and target organ damage.
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Graphene Aerogels Decorated with α-FeOOH Nanoparticles for Efficient Adsorption of Arsenic from Contaminated Waters.
TLDR
The prepared adsorbent showed outstanding absorption performance for the removal of As from contaminated water, because of its high surface-to-volume ratio and characteristic pore network in the 3D architecture.
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Eicosapentaenoic acid metabolism by cytochrome P450 enzymes of the CYP2C subfamily.
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A Peroxisome Proliferator-Activated Receptor-α Activator Induces Renal CYP2C23 Activity and Protects from Angiotensin II-Induced Renal Injury
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Dietary n-3 Polyunsaturated Fatty Acids and Direct Renin Inhibition Improve Electrical Remodeling in a Model of High Human Renin Hypertension
TLDR
N-3 PUFAs and aliskiren improved electrical remodeling, arrhythmia induction, and connexin 43 expression, despite a 70-mm Hg difference in blood pressure and the development of cardiac hypertrophy.
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A peroxisome proliferator-activated receptor-alpha activator induces renal CYP2C23 activity and protects from angiotensin II-induced renal injury.
TLDR
It is proposed that CYP-dependent EET/HEET production may serve as an anti-inflammatory control mechanism and Feno protects against angiotensin II-induced renal damage and acts as inducer of CYP2C23-mediated epoxygenase activities.
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Wild fire impact on copper, zinc, lead and cadmium distribution in soil and relation with abundance in selected plants of Lamiaceae family from Vidlic Mountain (Serbia).
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Characterization of lead sorption by the natural and Fe(III)-modified zeolite
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Effects of cutting type and a method of IBA application on rooting of softwood cuttings from elite tree of Cornelian cherry (Cornus mas L.) from Belgrade area.
In this study, the effect of application method of indole-3-butyric acid (IBA) (powder dip or immersion in the solution) on rooting of softwood cuttings of Cornelian cherry was examined. Four types…
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