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Ex vivo generation of fully mature human red blood cells from hematopoietic stem cells
We describe here the large-scale ex vivo production of mature human red blood cells (RBCs) from hematopoietic stem cells of diverse origins. By mimicking the marrow microenvironment through theExpand
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Fine-grained sediment in river systems : Environmental significance and management issues
Fine-grained sediment is a natural and essential component of river systems and plays a major role in the hydrological, geomorphological and ecological functioning of rivers. In many areas of theExpand
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Biochemical Characterization and Ligand Binding Properties of Neuroglobin, a Novel Member of the Globin Family*
Neuroglobin is a recently discovered member of the globin superfamily that is suggested to enhance the O2 supply of the vertebrate brain. Spectral measurements with human and mouse recombinantExpand
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Human erythroid cells produced ex vivo at large scale differentiate into red blood cells in vivo
New sources of red blood cells (RBCs) would improve the transfusion capacity of blood centers. Our objective was to generate cells for transfusion by inducing a massive proliferation of hematopoieticExpand
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Tectonic and paleoclimatic significance of Quaternary river terraces of the Waipaoa river, east coast, North Island, New Zealand
Abstract Remnants of four aggradational terraces in the lower 45 km of the main branch of the Waipaoa River have been correlated with cold/cool climate episodes of the Otiran glaciation. The youngestExpand
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Afforestation/reforestation of New Zealand marginal pasture lands by indigenous shrublands: the potential for Kyoto forest sinks
La Nouvelle-Zelande va utiliser les provisions de boisement/reboisement (A/R) de l'article 3.3 du protocole de Kyoto pour compenser les emissions de gaz a effets de serre, pendant la premiere periodeExpand
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The Redox State of the Cell Regulates the Ligand Binding Affinity of Human Neuroglobin and Cytoglobin*
Neuroglobin and cytoglobin reversibly bind oxygen in competition with the distal histidine, and the observed oxygen affinity therefore depends on the properties of both ligands. In the absence of anExpand
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Gully erosion in Mangatu Forest, New Zealand, estimated from digital elevation models
The methodology and errors involved in determining the amount of sediment produced during two (19·5 and 33·2 year) periods by 11 (c. 0·01 − >0·20 km2) gullies within a 4 km2 area in the headwaters ofExpand
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Heme-based sensors, exemplified by the kinase FixL, are a new class of heme protein with distinctive ligand binding and autoxidation.
FixL's are chimeric heme protein kinases from symbiotic nitrogen-fixing Rhizobia. We have overexpressed three FixL variants in Escherichia coli. Bradyrhizobium japonicum FixL, a soluble dimericExpand
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Land-use change, sediment production and channel response in upland regions
Human-induced modifications of the vegetation cover in river basins may cause strong geomorphic responses by disturbing sediment supply, transport and deposition regimes. The response is particularlyExpand
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