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Effect of dutasteride on the risk of prostate cancer.
- G. Andriole, D. Bostwick, +11 authors R. Rittmaster
- The New England journal of medicine
- 8 April 2010
Over the course of the 4-year study period, dutasteride reduced the risk of incident prostate cancer detected on biopsy and improved the outcomes related to benign prostatic hyperplasia. Expand
Bladder tumor markers beyond cytology: International Consensus Panel on bladder tumor markers.
The International Consensus Panel on cytology and bladder tumor markers found that the most practical use of noninvasive tests is to monitor bladder cancer recurrence, thereby reducing the number of surveillance cystoscopies performed each year. Expand
The controversial relationship between benign prostatic hyperplasia and prostate cancer: the role of inflammation.
Evidence in the peer-reviewed literature suggested that chronic prostatic inflammation may be involved in the development and progression of Chronic prostatic disease, such as BPH and PCa, although there is still no evidence of a causal relation. Expand
Is benign prostatic hyperplasia (BPH) an immune inflammatory disease?
Data strongly suggest that BPH is an immune inflammatory disease, and unravelling the specific nature of immune dysregulation may help design novel drugs with these specific targets in mind. Expand
Differentiation between Cell Death Modes Using Measurements of Different Soluble Forms of Extracellular Cytokeratin 18
It is reported that soluble cytokeratin-18 (CK18) is released from human carcinoma cells during cell death, and cell death of epithelially derived tumors can be assessed in patient serum, suggesting that tumor apoptosis may not necessarily be the dominating death mode in many tumors in vivo. Expand
Clinical utility of the PCA3 urine assay in European men scheduled for repeat biopsy.
The PCA3 score was superior to %fPSA for predicting repeat prostate biopsy outcome and may be indicative of clinical stage and significance of pCa. Expand
Improved detection of urothelial carcinoma in situ with hexaminolevulinate fluorescence cystoscopy.
- J. Schmidbauer, F. Witjes, N. Schmeller, R. Donat, M. Susani, M. Marberger
- The Journal of urology
HAL fluorescence cystoscopy improves the detection of bladder CIS significantly, which has consequences for clinical management and may improve the patient prognosis. Expand
Prospective evaluation of prostate cancer detected on biopsies 1, 2, 3 and 4: when should we stop?
Investigation of biochemical parameters and pathological features, as well as biopsy related morbidity of prostate cancer detected on biopsies 2, 3 and 4 in men with total serum prostate specific antigen (PSA) suggested comparable biological behaviors. Expand
Optimal predictors of prostate cancer on repeat prostate biopsy: a prospective study of 1,051 men.
Nine out of 10 patients with negative initial prostatic biopsy results will be diagnosed with prostate cancer on repeat biopsy, and percent free PSA was the most accurate predictor of prostate cancer in repeatBiopsy specimens. Expand