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Apoptosis in tumors and normal tissues induced by whole body hyperthermia in rats.
Apoptosis in tumor and normal tissues was examined in rats treated with whole-body hyperthermia (WBH; 41.5 degrees C for 2 h). WBH alone produced 0.5 day of tumor growth delay (TGD) in a fibrosarcoma… Expand
Prognostic significance of reverse transcriptase‐polymerase chain reaction measurement of carcinoembryonic antigen mRNA levels in tumor drainage blood and peripheral blood of patients with colorectal…
The objective of this study was to assess the prognostic value of detecting circulating tumor cells in the tumor drainage blood and peripheral blood of patients with colorectal carcinoma.
Lipid peroxidation levels in rat cardiac muscle are affected by age and thyroid status.
Free radicals, hydroxyperoxides and H(2)O(2) are all known to damage cell components. This study was designed to compare the concentrations of hydroxyperoxide and free radical scavengers in the… Expand
Reduced Fhit expression is associated with mismatch repair deficiency in human advanced colorectal carcinoma
- H. Andachi, K. Yashima, +10 authors Y. Murawaki
- Biology, Medicine
- British Journal of Cancer
- 12 August 2002
The Fragile Histidine Triad gene, encompassing the FRA3B fragile site at chromosome 3p14.2, is a candidate tumour suppressor gene involved in multiple tumour types including colorectal carcinomas.… Expand
Changes in superoxide dismutase activities and concentrations and myeloperoxidase activities in leukocytes from patients with diabetes mellitus.
- K. Uchimura, A. Nagasaka, +10 authors M. Itoh
- Journal of diabetes and its complications
- 1 September 1999
To investigate whether the two free-radical scavengers, Cu, Zn- and Mn-superoxide dismutase (SOD), are changed in leukocytes of diabetic patients, and the alteration of these enzymes correlates with… Expand
Haematological toxicity of carboplatin and cisplatin combined with whole body hyperthermia in rats.
Acute haematological toxicity induced by cis-diammine-1,1-cyclobutane dicarboxylate platinum (II) (carboplatin) and cis-diamminedichloroplatinum (II) (cisplatin) in combination with whole body… Expand
Circadian rhythms of cardiovascular functions are modulated by the baroreflex and the autonomic nervous system in the rat.
- M. Makino, H. Hayashi, H. Takezawa, M. Hirai, H. Saito, S. Ebihara
- 2 September 1997
BACKGROUND We assessed the hypothesis that the baroreflex and the autonomic nervous system are important in the control of the circadian rhythms of cardiovascular functions. METHODS AND RESULTS We… Expand
Effects of prolactins on the chromatophores of the tilapia, Oreochromis niloticus.
- K. Kitta, M. Makino, N. Oshima, H. Bern
- Biology, Medicine
- General and comparative endocrinology
- 1 December 1993
Using isolated scales and split-fin preparations of the tilapia Oreochromis niloticus, the effects of a pair of prolactins of the tilapia Oreochromis mossambicus (tPRL177 and tPRL188) and of ovine… Expand
Reduced E-cadherin expression and enlargement of cancer nuclei strongly correlate with hematogenic metastasis in colorectal adenocarcinoma.
- M. Ikeguchi, T. Taniguchi, M. Makino, N. Kaibara
- Scandinavian journal of gastroenterology
- 1 August 2000
BACKGROUND Synchronous and metachronous hematogenic metastases are frequently detected in patients with colorectal carcinoma. Once these metastases have developed, the prognoses of patients are poor.… Expand
High incidence of liver metastasis in gastric cancer with medullary growth pattern
- N. Kaibara, O. Kimura, H. Nishidoi, M. Makino, H. Kawasumi, S. Koga
- Journal of surgical oncology
- 1 March 1985
We studied the histology of resected specimens from 71 gastric cancer patients with synchronous and metachronous liver metastasis to assess the predominance of a particular histological pattern in… Expand