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Embryonic Lethality in Mice Lacking the Nuclear Factor of Activated T Cells 5 Protein Due to Impaired Cardiac Development and Function
- M. Mak, K. Lam, +6 authors Sookja K. Chung
- Biology, Medicine
- PloS one
- 12 July 2011
Nuclear factor of activated T cells 5 protein (NFAT5) is thought to be important for cellular adaptation to osmotic stress by regulating the transcription of genes responsible for the synthesis or… Expand
Ubiquitination of p53 at Multiple Sites in the DNA-Binding Domain
- Wan Chan, M. Mak, T. Fung, A. Lau, W. Y. Siu, R. Poon
- Biology, Medicine
- Molecular Cancer Research
- 1 January 2006
The tumor suppressor p53 is negatively regulated by the ubiquitin ligase MDM2. The MDM2 recognition site is at the NH2-terminal region of p53, but the positions of the actual ubiquitination acceptor… Expand
Ubiquitination of p 53 at Multiple Sites in the DNA-Binding Domain
The tumor suppressor p53 is negatively regulated by the ubiquitin ligase MDM2. The MDM2 recognition site is at the NH2-terminal region of p53, but the positions of the actual ubiquitination acceptor… Expand
Title Embryonic lethality in mice lacking the nuclear factor of activated t cells 5 protein due to impaired cardiac development and function
- M. Mak, K. Lam, +7 authors Sookja K. Chung
- 2011
Nuclear factor of activated T cells 5 protein (NFAT5) is thought to be important for cellular adaptation to osmotic stress by regulating the transcription of genes responsible for the synthesis or… Expand