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Human melatonin and alerting response to blue-enriched light depend on a polymorphism in the clock gene PER3.
First evidence is provided that humans homozygous for the PER3 5/5 allele are particularly sensitive to blue-enriched light, as indexed by the suppression of endogenous melatonin and waking theta activity.
Pushing the Limits: Chronotype and Time of Day Modulate Working Memory-Dependent Cerebral Activity
The hypothesis that higher task complexity leads to a chronotype-dependent increase in thalamic and frontal brain activity, permitting stabilization of working memory performance across the day is supported.
Effects of Artificial Dawn and Morning Blue Light on Daytime Cognitive Performance, Well-being, Cortisol and Melatonin Levels
Exposure to an artificial morning dawn simulation light improves subjective well-being, mood, and cognitive performance, as compared with DL and BL, with minimal impact on circadian phase.
Sleep EEG alterations: effects of pulsed magnetic fields versus pulse‐modulated radio frequency electromagnetic fields
It is demonstrated that both pulse‐modulated radio frequency and pulsed magnetic fields affect brain physiology, and the presence of significant frequency components above 20 Hz are not fundamental for these effects to occur.
Sleep ability mediates individual differences in the vulnerability to sleep loss: Evidence from a PER3 polymorphism
Dawn simulation light impacts on different cognitive domains under sleep restriction
Insights into Behavioral Vulnerability to Differential Sleep Pressure and Circadian Phase from a Functional ADA Polymorphism
These data confirm the assumption that interindividual differences regarding the effect of sleep manipulation highly depend on the cognitive task and circadian phase and thus emphasize the necessity of a multimethodological approach and indicate that napping might be suitable to counteract endogenously heightened sleep pressure depending on the neurobehavioral domain.
SLEEP-WAKE RHYTHMS AND COGNITION
Regarding the presence of prominent inter-individual variability in sleep-wake behaviors and its impact on cognition and subjective wellbeing, individually tailored schemes might be more accurate, also for the prediction of treatment efficiency at the clinical level.
Prevalence and management of chronic insomnia in Swiss primary care: Cross‐sectional data from the “Sentinella” practice‐based research network
Reducing the burden of insomnia depends on disseminating knowledge about and access to CBT‐I, and encouraging PCPs to discuss it with and offer it as a first‐line treatment to patients with chronic insomnia.