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Intravenous thrombolysis with recombinant tissue plasminogen activator for acute hemispheric stroke. The European Cooperative Acute Stroke Study (ECASS)
TLDR
Intravenous thrombolysis in acute ischemic stroke is effective in improving some functional measures and neurologic outcome in a defined subgroup of stroke patients with moderate to severe neurologic deficit and without extended infarct signs on the initial CT scan, however, the identification of this subgroup is difficult. Expand
Neurological and functional recovery in human stroke are associated with peripheral blood CD34+ cell mobilization
TLDR
The mobilization of PB-MNC-CD34+ cells might be predictive of neurological and functional recovery in patients with acute cerebral ischemic stroke. Expand
Penumbral imaging and functional outcome in patients with anterior circulation ischaemic stroke treated with endovascular thrombectomy versus medical therapy: a meta-analysis of individual
TLDR
Estimated ischaemic core volume was independently associated with functional independence and functional improvement but did not modify the treatment benefit of endovascular thrombectomy over standard medical therapy for improved functional outcome. Expand
Score for the Targeting of Atrial Fibrillation (STAF): A New Approach to the Detection of Atrial Fibrillation in the Secondary Prevention of Ischemic Stroke
TLDR
STAF can be used as part of a novel and simple strategy for the targeting of AF in the secondary prevention of ischemic stroke and is required to validate in a larger number of patients. Expand
Optimal timing and duration of continuous electrocardiographic monitoring for detecting atrial fibrillation in stroke patients.
TLDR
It is suggested that in order to enhance the detection rate of AF, CEM could be generalized in the stroke unit and must be started early in patients with acute stroke and prolonged over a minimum of 4 days. Expand
Ozone air pollution and ischaemic stroke occurrence: a case-crossover study in Nice, France
TLDR
The results confirm the relationship between low-level O3 exposure and ischaemic stroke in high vascular risk subgroup with linear exposure–response relation, independently of other pollutants and meteorological parameters. Expand
A Comparison of Two LDL Cholesterol Targets after Ischemic Stroke.
TLDR
After an ischemic stroke or TIA with evidence of atherosclerosis, patients who had a target LDL cholesterol level of less than 70 mg per deciliter had a lower risk of subsequent cardiovascular events than those whoHad a target range of 90 mg to 110 mg perDeciliter. Expand
Imaging features and safety and efficacy of endovascular stroke treatment: a meta-analysis of individual patient-level data
TLDR
The overall treatment effect favoured EVT (adjusted common odds ratio [cOR] for a shift towards better outcome on the mRS 2·00, 95% CI 1·69-2·38; p<0·0001) and EVT achieved better outcomes at 90 days than standard medical therapy alone across a broad range of baseline imaging categories. Expand
Estimating the Cost-Effectiveness of Stroke Units in France Compared With Conventional Care
TLDR
The cost-effectiveness ratio for stroke units is much lower than the threshold of acceptability recognized by the international scientific community, which justifies organizational changes in the management of stroke patients and the establishment of stroke units in France. Expand
Multiple Cerebral Aneurysms Caused by Cardiac Myxoma
TLDR
A case of multiple cerebral aneurysms caused by left atrial myxoma is reported and the hypothetical pathogenesis, radiological aspects and treatment of these neoplastic aneurYSms are discussed. Expand
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