This paper reports a study of the chemistry of valinomycin, enniatins and related membrane-active depsipeptides that increase alkali metal ion permeability of model and biological membranes. The… (More)
Auf Grund eines grossen Vergleichsmaterials wurden die Strukturelemente, die für die antimikrobielle Aktivität der Cyclodepsipeptide nötig sind, ermittelt. Insbesondere wurden Ringgrösse, Ersatz der… (More)
THE interaction of a biologically active substance with a selective receptor (for instance, substrate and enzyme) to cause a certain physiological effect is chemically complex, requiring not only a… (More)
SINCE 1953 several antibiotics of similar biological and physico-chemical properties have been described. These are aureolic acid1, aburamycin2, LA-7017 (ref. 3), M5-18903 (ref. 4), chromomycin5,… (More)