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Exodus of 42K+ and 86Rb+ from rat thymic and human blood lymphocytes exposed to phytohemagglutinin
86Rb+ efflux was increased by 27% in rat thymic lymphocytes and by 78% in human blood lymphocytes following PHA treatment, and the rate constant for efflux, Ke, was significantly increased by PHA. Expand
A rapid phytohemagglutinin induced alteration in lymphocyte potassium permeability
Findings indicate that phytohemagglutinin produces a rapid alteration in lymphocyte plasma membranes so as to allow abnormal K+ exchange, which is of importance because investigators who measure intracellular solutes in phy tohemag GLUTinin‐treated lymphocytes must consider the possibility of loss during preparative washes. Expand
Conversion of canavanine to α-keto-γ-guanidinooxybutyrate and to vinylglyoxylate and 2-hydroxyguanidine
Abstract It was observed previously that hydroxyguanidine is formed in the reaction of canavanine(2-amino-4-guanidinooxybutanoate) with amino acid oxidases. The present work shows thatExpand
Human lymphocyte potassium content during the initiation of phytohemagglutinin‐induced mitogenesis
It is shown that K+ does not change for 24 hours following PHA treatment, which may be a compensatory change for an increased exodus, explaining the failure of K+ to change following lectin treatment. Expand
The psychological concomitants of plastic surgery.
Cosmetic surgery of the eyelids and forehead.
Conversion of canavanine to alpha-keto-gamma-guanidinooxybutyrate and to vinylglyoxylate and 2-hydroxyguanidine.
The present work shows that hydroxyguanidine is formed by a nonenzymatic beta,gamma-elimination reaction following enzymatic oxidation at the alpha-C and that the abstraction of the beta-H is general-base catalyzed. Expand