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Structural insights into the recognition of phosphorylated FUNDC1 by LC3B in mitophagy
Mitophagy is an essential intracellular process that eliminates dysfunctional mitochondria and maintains cellular homeostasis. Mitophagy is regulated by the post-translational modification ofExpand
A conserved dimer interface connects ERH and YTH family proteins to promote gene silencing
Gene regulatory mechanisms rely on a complex network of RNA processing factors to prevent untimely gene expression. In fission yeast, the highly conserved ortholog of human ERH, called Erh1,Expand
Structural insights reveal the specific recognition of roX RNA by the dsRNA-binding domains of the RNA helicase MLE and its indispensable role in dosage compensation in Drosophila
Abstract In Drosophila, dosage compensation globally upregulates the expression of genes located on male single X-chromosome. Maleless (MLE) helicase plays an essential role to incorporate the roXExpand
Insights into the Structure of Dimeric RNA Helicase CsdA and Indispensable Role of Its C-Terminal Regions.
CsdA has been proposed to be essential for the biogenesis of ribosome and gene regulation after cold shock. However, the structure of CsdA and the function of its long C-terminal regions are stillExpand
Crystal structure of Arabidopsis terminal uridylyl transferase URT1.
  • L. Zhu, Qian Hu, +6 authors Q. Gong
  • Chemistry, Medicine
  • Biochemical and biophysical research…
  • 30 January 2020
3' uridylation is an essential modification associated with coding and noncoding RNA degradation in eukaryotes. In Arabidopsis, HESO1 was first identified as the major nucleotidyl transferase thatExpand
Structural insights reveal the specific recognition of roX RNA by the dsRNA-binding domains of the RNA helicase MLE and its indispensable role in dosage compensation in Drosophila.
In Drosophila, dosage compensation globally upregulates the expression of genes located on male single X-chromosome. Maleless (MLE) helicase plays an essential role to incorporate the roX lncRNA intoExpand
Crystal Structure Of of PHF20L1 Tudor1 Y24L mutant
PHF20L1 Tudor1 - MES
Structural and biochemical insights into the recognition of RNA helicase CGH-1 by CAR-1 in C. elegans.
A protein-RNA complex containing the RNA helicase CGH-1 and a germline specific RNA-binding protein CAR-1 is involved in various aspects of function in C. elegans. However, the structural basis forExpand
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