Share This Author
Targeted mutation of plasma phospholipid transfer protein gene markedly reduces high-density lipoprotein levels.
Reduced plasma PLTP activity causes markedly decreased HDL lipid and apoprotein, demonstrating the importance of transfer of surface components of TRL in the maintenance of HDL levels.
Microsomal triglyceride transfer protein.
Microsomal triglyceride transfer protein (MTP) regulation in HepG2 cells: insulin negatively regulates MTP gene expression.
MTP mRNA levels are acutely regulated by insulin in HepG2 cells; however, sustained changes in MTP RNA levels would be required to affect MTP protein levels.
The cis-acting phorbol ester "12-O-tetradecanoylphorbol 13-acetate"-responsive element is involved in shear stress-induced monocyte chemotactic protein 1 gene expression.
- J. Shyy, M. Lin, J. Han, Y. Lu, M. Petrime, S. Chien
- BiologyProceedings of the National Academy of Sciences…
- 15 August 1995
A molecular basis for the transient induction of MCP-1 gene by shear stress is provided and site-specific mutations on two sites demonstrated that the proximal one (TGACTCC) but not the distal one (TCACTCA) was shear-responsive, suggesting that shear Stress and TPA share a similar signal transduction pathway in activating cells.
Adsorption of acid dye onto activated carbons prepared from agricultural waste bagasse by ZnCl2 activation.
Shear stress induction of the tissue factor gene.
The findings suggest that the shear stress induction of TF gene expression is mediated through an increased Sp1 transcriptional activity with a concomitant hyperphosphorylation of Sp1.
Channel formation in planar lipid bilayers by a neurotoxic fragment of the beta-amyloid peptide.
It is demonstrated that a neurotoxic fragment of A beta, A beta (25-35) spontaneously inserted into planar lipid membranes to form weakly selective, voltage dependent, ion-permeable channels.
CN radical reactions with hydrogen cyanide and cyanogen - Comparison of theory and experiment
Absolute rate constants were obtained for CN radical reactions with HCN and C2N2 employing the method of laser photolysis/laser induced fluorescence. The rate constants were found to be temperature…
Role of adenine and guanine nucleotides in the activity and response of adenylate cyclase systems to hormones: evidence for multisite transition states.
Cloning and regulation of hamster microsomal triglyceride transfer protein. The regulation is independent from that of other hepatic and intestinal proteins which participate in the transport of…