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Cancer prevention by bovine lactoferrin and underlying mechanisms--a review of experimental and clinical studies.
In experimental studies, bovine lactoferrin (bLF) has been found to significantly inhibit colon, esophagus, lung, and bladder carcinogenesis in rats when administered orally in the post-initiationExpand
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Chemopreventive Effects of β‐Carotene, α‐Tocopherol and Five Naturally Occurring Antioxidants on Initiation of Hepatocarcinogenesis by 2‐Amino‐3‐methylimidazo[4,5‐f] qumoline in the Rat
Inhibitory effects of naturally occurring antioxidants on the initiation stage of hepatocarcinogenesis were studied. Group 1 rats were given a diet containing β‐carotene (β8‐CT, 0.02%), α‐tocopherolExpand
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Organotropic Chemopreventive Effects of n‐3 Unsaturated Fatty Acids in a Rat Multi‐organ Carcinogenesis Model
Organotropic chemopreventive effects of n‐3 unsaturated fatty acids were studied using a multi‐organ carcinogenesis model in male rats. Rats were treated with diethylnitrosamine (DEN),Expand
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Antimetastatic and antitumor effects of 2,4-diamino-6-(pyridine-4-yl)-1,3,5-triazine (4PyDAT) on the high lung metastatic colon 26 tumor in mice.
The therapeutic potential of a diaminotriazine, 2,4-diamino-6-(pyridine-4-yl)-1,3,5-triazine (4PyDAT), was investigated in a metastatic model using the mouse colon 26 carcinoma variant (Co26Lu),Expand
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Synergistic effect of recombinant interleukin-2 on the inhibition of growth of adenocarcinoma 755 by mitomycin.
The increase in life-span (ILS) of tumor-bearing mice caused by recombinant interleukin-2 (RIL-2) was studied in the solid tumor adenocarcinoma 755 system. With long-term treatment (Days 5-12), RIL-2Expand
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Effects of interleukin-2 and interferon-alpha A/D treatment on lymphocytes from tumour-bearing mice.
The in vivo antitumour activities of recombinant human interleukin-2 (rHIL-2) and recombinant human hybrid interferon alpha A/D (rIFN-alpha A/D) were tested in relation to adenocarcinoma 755. TheExpand
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Therapeutic activity and tissue distribution of ME2303, a new anthracycline containing fluorine, and its metabolites in mice bearing hepatic metastases of Lewis lung carcinoma
Doxorubicin (DXR) and ME2303, a new fluorine-containing (C'-2) anthracycline derivative, were studied for their tissue distributions—particularly in the plasma, liver and bone marrow—followingExpand
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Antitumor effect and tumor level of 5‐fluoro‐2‐deoxyuridylate following oral administration of tetradecyl 2'‐deoxy‐5‐fluoro‐5'‐uridylate
The antltumor effect and tumor levels of 5-fluoro-2'-deoxyuridylate (FdUMP) following oral administration of tetradecyl 2'-deoxy-5-fluoro-5'-urldylate (TT-62) were compared with those attainedExpand
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