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Prevention and control of cystic echinococcosis.
Since the introduction of current (and past) hydatid control campaigns, there have been clear technological improvements made in the diagnosis and treatment of human and animal cystic echinococcosis, the diagnosis of canine echinocentrosis, and the genetic characterisation of strains and vaccination against Echinococcus granulosus in animals. Expand
Echinococcus granulosus sensu lato genotypes infecting humans--review of current knowledge.
Biological differences between the species and genotypes have potential to affect the transmission dynamics of the parasite, requiring modification of methods used in disease control initiatives. Expand
Subunit composition and specificity of the major cyst fluid antigens of Echinococcus granulosus.
The subunit composition and specificity of the major Echinococcus granulosus cyst fluid antigens were determined by immunochemical analysis using murine monoclonal antibodies against Antigen 5 andExpand
Neurocysticercosis: regional status, epidemiology, impact and control measures in the Americas.
The analysis of epidemiological data concerning human cysticercosis point to important advances in understanding the magnitude and distribution of this parasitic disease in Latin America, as well asExpand
Taenia solium taeniosis/cysticercosis in Africa: risk factors, epidemiology and prospects for control using vaccination.
The risk factors and epidemiology of T. solium cysticercosis in Africa, the main cause of acquired epilepsy in human population and results in considerable public health problems and economic costs to the endemic countries, are discussed and the options available for implementing control of this zoonotic disease are critically analyzed. Expand
Evaluation of three enzyme-linked immunosorbent assays (ELISAs) for the detection of serum antibodies in sheep infected with Echinococcus granulosus.
The ProtELISA was the most effective immunological method of those assessed for detection of infection with E. granulosus in sheep, demonstrating its limited diagnostic sensitivity of about 50-60%, which should be useful for the detection of the presence of infected sheep on a flock basis. Expand
Echinococcus multilocularis: developmental stage-specific expression of Antigen B 8-kDa-subunits.
Gene-specific RT-PCR and Western blot analyses revealed that these genes encoding 8-kDa subunit genes were expressed in a developmentally regulated manner in E. multilocularis vesicles, protoscoleces, and immature adult worms. Expand
Taenia saginata: vaccination against cysticercosis in cattle with recombinant oncosphere antigens.
Vaccination with a combination of two antigens induced up to 99.8% protection against experimental challenge infection with T. saginata eggs, and has the potential to be used on a commercial scale for the control of bovine cysticercosis. Expand
Variability in the Echinococcus granulosus cytochrome C oxidase 1 mitochondrial gene sequence from livestock in Turkey and a re-appraisal of the G1-3 genotype cluster.
Analysis of all GenBank entries for E. granulosus cox1 sequences representing G1, G2 and G3 genotypes identified substantial microsequence variability, which can be regarded as a microsequence variation of G3. Expand