• Publications
  • Influence
Cooperative regulation of cell polarity and growth by Drosophila tumor suppressors.
Loss of cell polarity and tissue architecture are characteristics of malignant cancers derived from epithelial tissues. We provide evidence from Drosophila that a group of membrane-associatedExpand
  • 838
  • 70
Kremen proteins are Dickkopf receptors that regulate Wnt/beta-catenin signalling.
The Wnt family of secreted glycoproteins mediate cell cell interactions during cell growth and differentiation in both embryos and adults. Canonical Wnt signalling by way of the beta-catenin pathwayExpand
  • 486
  • 47
Kremen proteins are Dickkopf receptors that regulate Wnt/β-catenin signalling
The Wnt family of secreted glycoproteins mediate cell–cell interactions during cell growth and differentiation in both embryos and adults. Canonical Wnt signalling by way of the β-catenin pathway isExpand
  • 813
  • 33
Stepwise formation of a SMAD activity gradient during dorsal-ventral patterning of the Drosophila embryo
Genetic evidence suggests that the Drosophila ectoderm is patterned by a spatial gradient of bone morphogenetic protein (BMP). Here we compare patterns of two related cellular responses, bothExpand
  • 71
  • 9
Improved prediction of lysine acetylation by support vector machines.
Reversible acetylation on lysine residues, a crucial post-translational modification (PTM) for both histone and non-histone proteins, governs many central cellular processes. Due to limited data andExpand
  • 69
  • 6
Role of Scrib and Dlg in anterior-posterior patterning of the follicular epithelium during Drosophila oogenesis
  • Q. Li, L. Shen, +6 authors M. Li
  • Medicine, Biology
  • BMC Developmental Biology
  • 1 December 2009
BackgroundProper patterning of the follicle cell epithelium over the egg chamber is essential for the Drosophila egg development. Differentiation of the epithelium into several distinct cell typesExpand
  • 16
  • 4
dBre1/dSet1-dependent pathway for histone H3K4 trimethylation has essential roles in controlling germline stem cell maintenance and germ cell differentiation in the Drosophila ovary.
The Drosophila ovarian germline stem cells (GSCs) constantly experience self-renewal and differentiation, ensuring the female fertility throughout life. The balance between GSC self-renewal andExpand
  • 35
  • 3
Rab11 is required during Drosophila eye development.
In an effort to identify the role of Rab11, a small GTP binding protein, during Drosophila differentiation, phenotypic manifestations associated with different alleles of Rab11 were studied. TheExpand
  • 44
  • 2
Medea SUMOylation restricts the signaling range of the Dpp morphogen in the Drosophila embryo.
Morphogens are secreted signaling molecules that form concentration gradients and control cell fate in developing tissues. During development, it is essential that morphogen range is strictlyExpand
  • 46
  • 2
S100A11: Diverse Function and Pathology Corresponding to Different Target Proteins
S100A11, as a member of S100 protein family, while featuring the common identities as the other EF-hand Ca2+-binding family members, has its own individual characteristics. S100A11 is widelyExpand
  • 51
  • 1