• Publications
  • Influence
The ASTRAL compendium for protein structure and sequence analysis
TLDR
The ASTRAL compendium provides several databases and tools to aid in the analysis of protein structures, particularly through the use of their sequences. Expand
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A simplified representation of protein conformations for rapid simulation of protein folding.
  • M. Levitt
  • Mathematics, Medicine
  • Journal of molecular biology
  • 14 June 1976
This report is one of a series of papers that introduce and use a new and highly simplified treatment of protein conformations. The first paper (Levitt & Warshel, 1975) outlined fhe approach andExpand
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The ASTRAL Compendium in 2004
TLDR
The ASTRAL Compendium provides several databases and tools to aid in the analysis of protein structures, particularly through the use of their sequences. Expand
  • 579
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A unified statistical framework for sequence comparison and structure comparison.
  • M. Levitt, M. Gerstein
  • Mathematics, Medicine
  • Proceedings of the National Academy of Sciences…
  • 26 May 1998
We present an approach for assessing the significance of sequence and structure comparisons by using nearly identical statistical formalisms for both sequence and structure. Doing so involves anExpand
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Accurate modeling of protein conformation by automatic segment matching.
  • M. Levitt
  • Physics, Medicine
  • Journal of molecular biology
  • 20 July 1992
Segment match modeling uses a data base of highly refined known protein X-ray structures to build an unknown target structure from its amino acid sequence and the atomic coordinates of a few of itsExpand
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Theoretical studies of enzymic reactions: dielectric, electrostatic and steric stabilization of the carbonium ion in the reaction of lysozyme.
Abstract A general method for detailed study of enzymic reactions is presented. The method considers the complete enzyme-substrate complex together with the surrounding solvent and evaluates all theExpand
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Structural patterns in globular proteins
A simple diagrammatic representation has been used to show the arrangement of α helices and β sheets in 31 globular proteins, which are classified into four clearly separated classes. The observedExpand
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Comprehensive assessment of automatic structural alignment against a manual standard, the scop classification of proteins
  • M. Gerstein, M. Levitt
  • Biology, Medicine
  • Protein science : a publication of the Protein…
  • 1 February 1998
TLDR
We apply a simple method for aligning protein sequences on the basis of a 3D structure, on a large scale, to the proteins in the scop classification of fold families. Expand
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Super-resolution biomolecular crystallography with low-resolution data
TLDR
We introduce a method that adds specific information from known homologous structures but allows global and local deformations of these homology models. Expand
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Decoys ‘R’ Us: A database of incorrect conformations to improve protein structure prediction
TLDR
The development of an energy or scoring function for protein structure prediction is greatly enhanced by testing the func–tion on a set of computer–generated conformations (decoys) to determine whether it can readily distinguish native–like conforma–tions from nonnative ones. Expand
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