M. Levitt

Publications
Influence

The ASTRAL compendium for protein structure and sequence analysis

S. Brenner, P. Koehl, M. Levitt
Biology, Computer Science
Nucleic Acids Res.
2000

The ASTRAL compendium provides several databases and tools to aid in the analysis of protein structures, particularly through the use of their sequences. Expand

A simplified representation of protein conformations for rapid simulation of protein folding.

M. Levitt
Mathematics, Medicine
Journal of molecular biology
14 June 1976

This report is one of a series of papers that introduce and use a new and highly simplified treatment of protein conformations. The first paper (Levitt & Warshel, 1975) outlined fhe approach and… Expand

The ASTRAL Compendium in 2004

J. Chandonia, G. Hon, +4 authors S. Brenner
Computer Science, Medicine
Nucleic Acids Res.
15 September 2003

The ASTRAL Compendium provides several databases and tools to aid in the analysis of protein structures, particularly through the use of their sequences. Expand

A unified statistical framework for sequence comparison and structure comparison.

M. Levitt, M. Gerstein
Mathematics, Medicine
Proceedings of the National Academy of Sciences…
26 May 1998

We present an approach for assessing the significance of sequence and structure comparisons by using nearly identical statistical formalisms for both sequence and structure. Doing so involves an… Expand

Accurate modeling of protein conformation by automatic segment matching.

M. Levitt
Physics, Medicine
Journal of molecular biology
20 July 1992

Segment match modeling uses a data base of highly refined known protein X-ray structures to build an unknown target structure from its amino acid sequence and the atomic coordinates of a few of its… Expand

Theoretical studies of enzymic reactions: dielectric, electrostatic and steric stabilization of the carbonium ion in the reaction of lysozyme.

A. Warshel, M. Levitt
Chemistry, Medicine
Journal of molecular biology
15 May 1976

Abstract A general method for detailed study of enzymic reactions is presented. The method considers the complete enzyme-substrate complex together with the surrounding solvent and evaluates all the… Expand

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Structural patterns in globular proteins

M. Levitt, C. Chothia
Chemistry, Medicine
Nature
1 June 1976

A simple diagrammatic representation has been used to show the arrangement of α helices and β sheets in 31 globular proteins, which are classified into four clearly separated classes. The observed… Expand

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Comprehensive assessment of automatic structural alignment against a manual standard, the scop classification of proteins

M. Gerstein, M. Levitt
Biology, Medicine
Protein science : a publication of the Protein…
1 February 1998

We apply a simple method for aligning protein sequences on the basis of a 3D structure, on a large scale, to the proteins in the scop classification of fold families. Expand

Super-resolution biomolecular crystallography with low-resolution data

G. Schröder, M. Levitt, A. Brünger
Physics, Medicine
Nature
18 February 2010

We introduce a method that adds specific information from known homologous structures but allows global and local deformations of these homology models. Expand

Decoys ‘R’ Us: A database of incorrect conformations to improve protein structure prediction

R. Samudrala, M. Levitt
Computer Science, Medicine
Protein science : a publication of the Protein…
2000

The development of an energy or scoring function for protein structure prediction is greatly enhanced by testing the func–tion on a set of computer–generated conformations (decoys) to determine whether it can readily distinguish native–like conforma–tions from nonnative ones. Expand

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