M. Lesh

Publications206
h-index57
Citations11,748
Highly Influential Citations212
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Percutaneous left atrial appendage transcatheter occlusion (PLAATO system) to prevent stroke in high-risk patients with non-rheumatic atrial fibrillation: results from the international multi-center…
OBJECTIVES These studies were conducted to evaluate the feasibility of percutaneous left atrial appendage (LAA) occlusion using the PLAATO system (ev3 Inc., Plymouth, Minnesota). BACKGROUND… Expand
  • 447
  • 13
Use of P wave configuration during atrial tachycardia to predict site of origin.
OBJECTIVES This study sought to construct an algorithm to differentiate left atrial from right atrial tachycardia foci on the basis of surface electrocardiograms (ECGs). BACKGROUND Atrial… Expand
  • 252
  • 10
  • PDF
Role of right atrial endocardial structures as barriers to conduction during human type I atrial flutter. Activation and entrainment mapping guided by intracardiac echocardiography.
BACKGROUND The importance of barriers in atrial flutter has been demonstrated in animals. We used activation and entrainment mapping, guided by intracardiac echocardiography (ICE), to determine… Expand
  • 484
  • 9
Percutaneous Left Atrial Appendage Transcatheter Occlusion to Prevent Stroke in High-Risk Patients With Atrial Fibrillation: Early Clinical Experience
Background—Thromboembolism due to atrial fibrillation (AF) is a frequent cause of stroke. More than 90% of thrombi in AF form in the left atrial appendage (LAA). Obliteration of the appendage may… Expand
  • 412
  • 8
  • PDF
Activation and entrainment mapping defines the tricuspid annulus as the anterior barrier in typical atrial flutter.
BACKGROUND The importance of anatomic barriers in the atrial flutter reentry circuit has been well demonstrated in canine models. It has been shown previously that the crista terminalis and its… Expand
  • 333
  • 8
"Cristal tachycardias": origin of right atrial tachycardias from the crista terminalis identified by intracardiac echocardiography.
OBJECTIVES We sought to use intracardiac echocardiography (ICE) to identify the anatomic origin of focal right atrial tachycardias and to define their relation with the crista terminalis (CT). … Expand
  • 313
  • 7
  • PDF
Autonomic nervous system and sudden cardiac death.
  • H. Barron, M. Lesh
  • Medicine
  • Journal of the American College of Cardiology
  • 1 April 1996
In the United States, sudden cardiac death is a major public health problem, accounting for approximately 300,000 deaths annually. Accurate identification of those patients at highest risk for this… Expand
  • 437
  • 6
Radiofrequency catheter ablation as a cure for idiopathic tachycardia of both left and right ventricular origin.
OBJECTIVES The purpose of this study was 1) to investigate the efficacy and safety of radiofrequency energy catheter ablation as curative treatment for idiopathic tachycardia of both left and right… Expand
  • 400
  • 6
Ablation of 'incisional' reentrant atrial tachycardia complicating surgery for congenital heart disease. Use of entrainment to define a critical isthmus of conduction.
BACKGROUND Intra-atrial reentrant tachycardia occurs frequently after surgery for congenital heart disease and is difficult to treat. We tested the hypotheses that intra-atrial reentrant tachycardia… Expand
  • 339
  • 6
Clinical Outcome after Radiofrequency Catheter Ablation of Focal Atrial Fibrillation Triggers
Ablation of Focal Atrial Fibrillation. Introduction: Ablative therapy for atrial fibrillation (AF) by targeting initiating triggers, usually in or around the pulmonary veins, has been reported by… Expand
  • 195
  • 6