• Publications
  • Influence
Transcatheter aortic-valve implantation for aortic stenosis in patients who cannot undergo surgery.
TLDR
In patients with severe aortic stenosis who were not suitable candidates for surgery, TAVI, as compared with standard therapy, significantly reduced the rates of death from any cause, the composite end point of deathFrom any cause or repeat hospitalization, and cardiac symptoms, despite the higher incidence of major strokes and major vascular events. Expand
Sirolimus-eluting stents versus standard stents in patients with stenosis in a native coronary artery.
TLDR
In this randomized clinical trial involving patients with complex coronary lesions, the use of a sirolimus-eluting stent had a consistent treatment effect, reducing the rates of restenosis and associated clinical events in all subgroups analyzed. Expand
A simple risk score for prediction of contrast-induced nephropathy after percutaneous coronary intervention: development and initial validation.
TLDR
The risk of CIN after PCI can be simply assessed using readily available information and can be used for both clinical and investigational purposes. Expand
Transcatheter or Surgical Aortic-Valve Replacement in Intermediate-Risk Patients.
TLDR
In intermediate-risk patients, TAVR was similar to surgical aortic-valve replacement with respect to the primary end point of death or disabling stroke; surgery resulted in fewer major vascular complications and less paravalvular aorta regurgitation. Expand
Outcomes associated with drug-eluting and bare-metal stents: a collaborative network meta-analysis
TLDR
A network meta-analysis with a mixed-treatment comparison method to combine direct within-trial comparisons between stents with indirect evidence from other trials while maintaining randomisation found sirolimus-eluting stents seem to be clinically better than bare-metal and paclitaxel-eluted stents. Expand
Transcatheter versus surgical aortic-valve replacement in high-risk patients.
TLDR
In high-risk patients with severe aortic stenosis, transcatheter and surgical procedures for aorti-valve replacement were associated with similar rates of survival at 1 year, although there were important differences in periprocedural risks. Expand
A controlled trial of renal denervation for resistant hypertension.
TLDR
This blinded trial did not show a significant reduction of systolic blood pressure in patients with resistant hypertension 6 months after renal-artery denervation as compared with a sham control. Expand
Safety and efficacy of sirolimus- and paclitaxel-eluting coronary stents.
TLDR
Stent thrombosis after 1 year was more common with both sirolimus-eluting stents and paclitaxel-eluted stents than with bare-metal stents, and both drug-elution stents were associated with a marked reduction in target-lesion revascularization. Expand
Updated standardized endpoint definitions for transcatheter aortic valve implantation: the Valve Academic Research Consortium-2 consensus document.
TLDR
This VARC-2 document has provided further standardization of endpoint definitions for studies evaluating the use of TAVI, which will lead to improved comparability and interpretability of the study results, supplying an increasingly growing body of evidence with respect to TAVi and/or surgical aortic valve replacement. Expand
...
1
2
3
4
5
...