• Publications
  • Influence
Mutations of the X-linked genes encoding neuroligins NLGN3 and NLGN4 are associated with autism
Many studies have supported a genetic etiology for autism. Here we report mutations in two X-linked genes encoding neuroligins NLGN3 and NLGN4 in siblings with autism-spectrum disorders. TheseExpand
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Promoting social behavior with oxytocin in high-functioning autism spectrum disorders
Social adaptation requires specific cognitive and emotional competences. Individuals with high-functioning autism or with Asperger syndrome cannot understand or engage in social situations despiteExpand
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Psychiatric and psychosocial problems in adults with normal-intelligence autism spectrum disorders
BackgroundIndividuals with autism spectrum disorders (ASDs) often display symptoms from other diagnostic categories. Studies of clinical and psychosocial outcome in adult patients with ASDs withoutExpand
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Diagnosing Autism: Analyses of Data from the Autism Diagnostic Interview
Results from ROC curves of items from two scales, the Autism Diagnostic Interview (ADI) and Autism Diagnostic Interview-Revised (ADI-R), operationalizing DSM-IV criteria for autism are presented forExpand
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Abnormal cortical voice processing in autism
Impairments in social interaction are a key feature of autism and are associated with atypical social information processing. Here we report functional magnetic resonance imaging (fMRI) resultsExpand
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Genome-Wide Scan for Autism Susceptibility Genes
Family and twin studies have suggested a genetic component in autism. We performed a genome-wide screen with 264 microsatellites markers in 51 multiplex families, using non-parametric linkageExpand
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Impaired decision making in suicide attempters.
OBJECTIVE The understanding of suicidal behavior is incomplete. The stress-diathesis model suggests that a deficit in serotonergic projections to the orbitofrontal cortex is involved inExpand
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Asperger's syndrome.
  • M. Leboyer
  • Medicine
  • The Harvard mental health letter
  • 2005
Keywords Disease name and synonyms Asperger syndrome Asperger disorder Definition Prevalence Abstract Asperger's syndrome (AS) was first described by Dr Hans Asperger, a pediatrician in Austria inExpand
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Can bipolar disorder be viewed as a multi-system inflammatory disease?
BACKGROUND Patients with bipolar disorder are known to be at high risk of premature death. Comorbid cardio-vascular diseases are a leading cause of excess mortality, well above the risk associatedExpand
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Longitudinal studies of cognition in schizophrenia: meta-analysis.
BACKGROUND A wide range of cognitive deficits have been demonstrated in schizophrenia, but their longitudinal course remains unclear. AIMS To bring together all the available information fromExpand
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