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Learning to Control a Brain–Machine Interface for Reaching and Grasping by Primates
Reaching and grasping in primates depend on the coordination of neural activity in large frontoparietal ensembles. Here we demonstrate that primates can learn to reach and grasp virtual objects byExpand
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Brain–machine interfaces: past, present and future
Since the original demonstration that electrical activity generated by ensembles of cortical neurons can be employed directly to control a robotic manipulator, research on brain-machine interfacesExpand
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Spontaneous cortical activity in awake monkeys composed of neuronal avalanches
Spontaneous neuronal activity is an important property of the cerebral cortex but its spatiotemporal organization and dynamical framework remain poorly understood. Studies in reduced systems—tissueExpand
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Principles of neural ensemble physiology underlying the operation of brain–machine interfaces
Research on brain–machine interfaces has been ongoing for at least a decade. During this period, simultaneous recordings of the extracellular electrical activity of hundreds of individual neuronsExpand
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Unscented Kalman Filter for Brain-Machine Interfaces
Brain machine interfaces (BMIs) are devices that convert neural signals into commands to directly control artificial actuators, such as limb prostheses. Previous real-time methods applied to decodingExpand
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Representation of Attended Versus Remembered Locations in Prefrontal Cortex
A great deal of research on the prefrontal cortex (PF), especially in nonhuman primates, has focused on the theory that it functions predominantly in the maintenance of short-term memories, andExpand
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Decoding of temporal intervals from cortical ensemble activity.
Neurophysiological, neuroimaging, and lesion studies point to a highly distributed processing of temporal information by cortico-basal ganglia-thalamic networks. However, there are virtually noExpand
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Extracting Kinematic Parameters for Monkey Bipedal Walking from Cortical Neuronal Ensemble Activity
The ability to walk may be critically impacted as the result of neurological injury or disease. While recent advances in brain–machine interfaces (BMIs) have demonstrated the feasibility ofExpand
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Chronic, Wireless Recordings of Large Scale Brain Activity in Freely Moving Rhesus Monkeys
Advances in techniques for recording large-scale brain activity contribute to both the elucidation of neurophysiological principles and the development of brain-machine interfaces (BMIs). Here weExpand
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Stable Ensemble Performance with Single-Neuron Variability during Reaching Movements in Primates
Significant variability in firing properties of individual neurons was observed while two monkeys, chronically implanted with multielectrode arrays in frontal and parietal cortical areas, performed aExpand
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