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Aberrant DNA methylation patterns of human spermatozoa in current smoker males.
- M. Laqqan, S. Tierling, Y. Alkhaled, C.Lo Porto, E. Solomayer, M. Hammadeh
- Biology, MedicineReproductive toxicology
- 1 August 2017
The results indicate that cigarette smoking causes biochemical changes in the sperm DNA methylation in many regions and could adversely affect semen parameters.
Impact of cigarette‐smoking on sperm DNA methylation and its effect on sperm parameters
- Y. Alkhaled, M. Laqqan, S. Tierling, C. Lo Porto, H. Amor, M. Hammadeh
- Biology, MedicineAndrologia
- 1 May 2018
A significant correlation between the variation in sperm DNA methylation level and standard sperm parameters in the case group was demonstrated and was demonstrated to be a positive correlation between cigarette‐smoking and sperm parameters.
Cigarette smoking induces only marginal changes in sperm DNA methylation levels of patients undergoing intracytoplasmic sperm injection treatment
- Y. Al Khaled, S. Tierling, M. Laqqan, C. Lo Porto, M. Hammadeh
- Biology, MedicineAndrologia
- 1 February 2018
This study could not detect biologically relevant CpG positions that are altered in sperm DNA methylation on the influence of cigarette smoking beyond individual‐specific effects that may be caused by other environmental factors.
Aberrations in sperm DNA methylation patterns are associated with abnormalities in semen parameters of subfertile males.
Three CpG sites showed the highest difference in methylation levels in sperm DNA methylation patterns and semen parameters in subfertile males compared to proven fertile males in this study.
Predictive value of soluble ST2 in adolescent and adult patients with complex congenital heart disease
In patients with complex CHD, sST2 may have additive value to natriuretic peptides for the prediction of all-cause mortality and combining both biomarkers and net reclassification improved with the addition of s ST2.
Spermatozoa from males with reduced fecundity exhibit differential DNA methylation patterns
- M. Laqqan, S. Tierling, Y. Alkhaled, C. Lo Porto, E. Solomayer, M. Hammadeh
- Biology, MedicineAndrology
- 23 May 2017
An alteration in themethylation levels of sperm DNA from males with reduced fecundity was observed, and an association between changes in the methylation level for these CpGs and different semen parameters has been found.
Alterations in sperm DNA methylation patterns of oligospermic males.
- M. Laqqan, S. Tierling, Y. Alkhaled, C. Loporto, M. Hammadeh
- Biology, MedicineReproductive biology
- 1 December 2017
It is shown that three CpG sites have a significant alteration in sperm DNA methylation levels in oligospermic males compared to proven fertile males, and these changes correlated with semen parameters.
Aberrations in sperm DNA methylation patterns of males suffering from reduced fecundity
An alteration in the methylation levels of sperm DNA from males with reduced fecundity was showed and a relationship between variations in themethylation level of these CpGs and sperm motility has been observed.
Relationship between nuclear DNA fragmentation, mitochondrial DNA damage and standard sperm parameters in spermatozoa of fertile and sub‐fertile men before and after freeze‐thawing procedure
In conclusion, freeze‐thawing process affects not only semen parameters but also n‐DNA and mt‐DNA, which could be used as sensitive parameters for assessment of the cryodamage of human spermatozoa.
Retracted: Influence of variation in global sperm DNA methylation level on the expression level of protamine genes and human semen parameters
- M. Laqqan, I. Ahmed, M. Yasin, M. Hammadeh, Yassin Maged
- Medicine, BiologyAndrologia
- 24 November 2019
Laqqan, M, Ahmed, I, Yasin, M, Hammadeh, ME, Yassin, M. Influence of variation in global sperm DNA methylation level on the expression level of protamine genes and human semen parameters. Andrologia.…