M. Landi

Publications17
h-index9
Citations296
Highly Influential Citations18
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Functional studies of the first selective beta 3-adrenergic receptor antagonist SR 59230A in rat brown adipocytes.
The SS-enantiomer 3-(2-ethylphenoxy)-1-[(1S)-1,2,3,4-tetrahy dronaphth-1-ylaminol]-(2S)-2-propanol oxalate (SR 59230A) is proposed to be the first beta 3-adrenergic receptor antagonist. The present… Expand
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SR146131: a new potent, orally active, and selective nonpeptide cholecystokinin subtype 1 receptor agonist. II. In vivo pharmacological characterization.
SR146131 is a potent and selective agonist at cholecystokinin subtype 1 (CCK1) receptors in vitro. The present study evaluates the activity of the compound in vivo. SR146131 completely inhibited… Expand
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Functional identification of rat atypical beta-adrenoceptors by the first beta 3-selective antagonists, aryloxypropanolaminotetralins.
1. We have assessed the relative abilities of compounds belonging to the new aryloxypropanolaminotetralin (APAT) class and of the reference beta-adrenoceptor-blocking agent, alprenolol, to antagonize… Expand
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Disposition of apomorphine in rat brain areas: relationship to stereotypy.
Apomorphine-induced stereotyped behavior and apomorphine levels in plasma, striatum and nucleus accumbens were determined in rats at various intervals after a single i.p. injection of serial doses of… Expand
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Neuronal NK3-receptors in guinea-pig ileum and taenia caeci: in vitro characterization by their first non-peptide antagonist, SR142801.
Abstract We investigated the ability of the first non-peptide tachykinin NK 3 -receptor antagonist, SR142801, to antagonize contractions of guinea-pig intestinal tissues induced by the putative… Expand
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Beta 3-adrenoceptors and intestinal motility.
Early substantial evidence of the low susceptibility to beta-adrenoceptor antagonists of non alpha-adrenergic responses reducing gut motility and tone was reluctantly accepted as indicating a third… Expand
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Field desorption mass spectra of rifamycins
The field desorption mass spectra of eight rifamycins were obtained and compared with their electron impact mass spectra. All the compounds gave abundant molecular or quasimolecular ions, while no… Expand
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Oral and intravenous pharmacokinetics of the peptidoleukotriene receptor antagonists SK&F S-106203 and 104353
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Determination of apomorphine in rat plasma and brain by high-performance liquid chromatography with electrochemical detection.
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Relative ability of N-methyl nalorphine and N-methyl levallorphan to prevent antinociception and intestinal transit inhibition in morphine treated rats.
Nalorphine, levallorphan and their quaternary analogs, N-(eq)allyl derivatives of the two diastereoisomers at the nitrogen atom (N-methyl nalorphine and N-methyl levallorphan) were tested for their… Expand
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