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Intramolecular and Intermolecular Interactions of Protein Kinase B Define Its Activation In Vivo
TLDR
In vivo studies provide a new model for the mechanism of activation of PKB, and takes a crucial widely studied regulator and addresses the fundamental question of the dynamic in vivo behaviour of P KB with a detailed molecular mechanism.
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Role of a Novel PH-Kinase Domain Interface in PKB/Akt Regulation: Structural Mechanism for Allosteric Inhibition
Protein kinase B (PKB/Akt) belongs to the AGC superfamily of related serine/threonine protein kinases. It is a key regulator downstream of various growth factors and hormones and is involved in…
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Afro-Caribbean Folk Medicine
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Diasporic Citizenship: Haitian Americans in Transnational America
List of tables - Introduction - Transnational Haiti - Of Convents, Congressmen, and Plessy v. Ferguson - Refugees and Immigrants - Headquarters and Subsidiary Households - Diasporic Business -…
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Location of Cholesterol in DMPC Membranes. A Comparative Study by Neutron Diffraction and Molecular Mechanics Simulation
The vertical location of 30 mol % cholesterol in a hydrated dimyristoylphosphatidylcholine (DMPC) membrane was determined by neutron diffraction on annealed samples containing deuterated or…
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A 3D structural and conformational study of procyanidin dimers in water and hydro‐alcoholic media as viewed by NMR and molecular modeling
TLDR
The finding of a predominant compact form for procyanidin dimers is discussed in relation with tannin‐saliva protein interactions that are of importance for the wine‐tasting/making processes.
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Voodoo and Politics in Haiti
Preface - Introduction: Religion and Politics - The Evolution of Colonial Voodoo from African to Slave Religions - Marronage and Voodoo - Revolutionary Voodoo Leaders - Secret Societies - Pilgrimage,…
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American Odyssey
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Three-dimensional structure and dynamics of wine tannin-saliva protein complexes. A multitechnique approach.
TLDR
B3 tannins with a "tweezers" conformation bind to the hydrophilic side of the saliva peptide, suggesting that the principal driving forces toward association are governed by hydrogen bonding between the carbonyl functions of proline residues and both the phenol and catechol OH groups.
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NMR and molecular modeling of wine tannins binding to saliva proteins: revisiting astringency from molecular and colloidal prospects
TLDR
NMR and molecular modeling of wine tannins binding to saliva proteins: revisiting astringency from molecular and colloidal prospects.
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