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- Franck Verrecchia, M. L. Chu, Alain Mauviel
- The Journal of biological chemistry
- 2001
Despite major advances in the understanding of the intimate mechanisms of transforming growth factor-beta (TGF-beta) signaling through the Smad pathway, little progress has been made in the… (More)
- Günter Kostka, Richard Giltay, +4 authors M. L. Chu
- Molecular and cellular biology
- 2001
The extracellular matrix protein fibulin-1 is a distinct component of vessel walls and can be associated with other ligands present in basement membranes, microfibrils, and elastic fibers. Its… (More)
- Daisuke Sawamura, K Li, M. L. Chu, J Uitto
- The Journal of biological chemistry
- 1991
Bullous pemphigoid antigens are defined as the autoantigens in a blistering skin disease, bullous pemphigoid. One of them, a 230-kDa protein (BPAG1), is associated with hemidesmosomes, attachment… (More)
- Takeshi Tsuda, Hui Wang, Rupert Dr. Timpl, M. L. Chu
- Developmental dynamics : an official publication…
- 2001
Previous studies showed that extracellular matrix protein, fibulin-2, is expressed during epithelial-mesenchymal transformation in the endocardial cushion matrix during embryonic heart development.… (More)
- Juha Peltonen, L L Hsiao, +5 authors Jouni Uitto
- The Journal of investigative dermatology
- 1991
Untreated, clinically active keloids were examined as model system to study the spatial expression of extracellular matrix and transforming growth factor-beta 1 (TGF-beta 1) genes in fibrotic skin… (More)
- Peter Ekblom, Marja Ekblom, +6 authors Rupert Dr. Timpl
- Development
- 1994
Recent biochemical studies suggested that the extracellular matrix protein nidogen is a binding molecule linking together basement membrane components. We studied its expression and role during… (More)
- Dieter P Reinhardt, Tsuguo Sasaki, +5 authors Lynn Y Sakai
- The Journal of biological chemistry
- 1996
Microfibrils 10-12 nm in diameter are found in elastic and non-elastic tissues with fibrillin as a major component. Little is known about the supramolecular structure of these microfibrils and the… (More)
- M. L. Chu, Jeanne C. Myers, Michael P. Bernard, J. F. Ding, Francesco Ramirez
- Nucleic acids research
- 1982
We report the cloning of five overlapping cDNAs bearing sequences specific for the human pro alpha 1(I) collagen chain. Poly-A RNA enriched for collagen sequences was purified from normal human… (More)
- Tung Chin Pan, Takuya Sasaki, Rui Zhi Zhang, Reinhard Fässler, Rupert Dr. Timpl, M. L. Chu
- The Journal of cell biology
- 1993
A new protein, fibulin-2, was predicted from sequence analysis of cDNA clones obtained from a mouse fibroblast library. This protein consists of a 1195-residue polypeptide preceded by a 26-residue… (More)
- Takako Sasaki, Helmut K. Wiedemann, Monika Matzner, M. L. Chu, Rupert Dr. Timpl
- Journal of cell science
- 1996
The extracellular matrix protein fibulin-2 was shown to be a typical product of cultured human and mouse fibroblasts by several immunological assays. It is secreted and deposited in cells and tissues… (More)