• Publications
  • Influence
Guidelines for the management of asymptomatic primary hyperparathyroidism: summary statement from the Fourth International Workshop.
OBJECTIVE Asymptomatic primary hyperparathyroidism (PHPT) is routinely encountered in clinical practices of endocrinology throughout the world. This report distills an update of current informationExpand
  • 387
  • 45
  • PDF
Strontium ranelate: dose-dependent effects in established postmenopausal vertebral osteoporosis--a 2-year randomized placebo controlled trial.
The aim of the strontium ranelate (SR) for treatment of osteoporosis (STRATOS) trial was to investigate the efficacy and safety of different doses of SR, a novel agent in the treatment ofExpand
  • 312
  • 20
Osteogenic Differentiation of Human Adipose Tissue‐Derived Stem Cells Is Modulated by the miR‐26a Targeting of the SMAD1 Transcription Factor
The molecular mechanisms that regulate hADSC differentiation toward osteogenic precursors and subsequent bone‐forming osteoblasts is unknown. Using osteoblast precursors obtained from subcutaneousExpand
  • 315
  • 18
Diagnosis of asymptomatic primary hyperparathyroidism: proceedings of the third international workshop.
OBJECTIVE Asymptomatic primary hyperparathyroidism (PHPT) is a common clinical problem. The purpose of this report is to guide the use of diagnostic tests for this condition in clinical practice. Expand
  • 174
  • 17
  • PDF
Genetics of osteoporosis: role of steroid hormone receptor gene polymorphisms
Osteoporosis is a common skeletal disease characterized by low bone mass and microarchitectural deterioration of bone tissue with a consequent increase in bone fragility and susceptibility toExpand
  • 95
  • 14
Vitamin D and estrogen receptor allelic variants in Italian postmenopausal women: evidence of multiple gene contribution to bone mineral density.
Bone mass and bone turnover are under genetic control. Restriction fragment length polymorphisms (RFLPs) at the vitamin D receptor (VDR) gene locus have been recently correlated to bone mineralExpand
  • 206
  • 9
A polymorphic CYP19 TTTA repeat influences aromatase activity and estrogen levels in elderly men: effects on bone metabolism.
Current evidence suggests that estrogen plays a dominant role in determining bone mineral density (BMD) in men, and inactivating mutations in the aromatase CYP19 gene have been associated with lowExpand
  • 148
  • 8
Management of Hypoparathyroidism: Present and Future.
CONTEXT Conventional management of hypoparathyroidism has focused upon maintaining the serum calcium with oral calcium and active vitamin D, often requiring high doses and giving rise to concernsExpand
  • 63
  • 8
  • PDF
Calcium sensing receptor signalling in physiology and cancer.
The calcium sensing receptor (CaSR) is a class C G-protein-coupled receptor that is crucial for the feedback regulation of extracellular free ionised calcium homeostasis. While extracellular calciumExpand
  • 108
  • 7
Familial hypocalciuric hypercalcemia and neonatal severe hyperparathyroidism. Effects of mutant gene dosage on phenotype.
Neonatal severe hyperparathyroidism is a rare life-threatening disorder characterized by very high serum calcium concentrations (> 15 mg/dl). Many cases have occurred in families with familialExpand
  • 237
  • 6
  • PDF