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Anthrax Spores Make an Essential Contribution to Vaccine Efficacy
ABSTRACT Anthrax is caused by Bacillus anthracis, a gram-positive spore-forming bacterium. Septicemia and toxemia rapidly lead to death in infected mammal hosts. Currently used acellular vaccinesExpand
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Strategy for the detection of Helicobacter species by amplification of 16S rRNA genes and identification of H. felis in a human gastric biopsy.
The aim of the present work was to develop polymerase chain reactions (PCRs) based on the conserved nucleotide sequence of the 16S rRNA gene for detection of bacteria of the Helicobacter genus inExpand
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Diversity among French Bacillus anthracis Isolates
ABSTRACT While outbreaks of animal anthrax zoonoses still regularly occur in France, little is known about the epidemiology links between them. We have used the eight-locus multilocus variable-numberExpand
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Functional Analysis of Bacillus anthracis Protective Antigen by Using Neutralizing Monoclonal Antibodies
ABSTRACT Protective antigen (PA) is central to the action of the lethal and edema toxins produced by Bacillus anthracis. It is the common cell-binding component, mediating the translocation of theExpand
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Fate of germinated Bacillus anthracis spores in primary murine macrophages
We investigated the fate of germinated Bacillus anthracis spores after their germination in Swiss murine peritoneal macrophages and in the cell line RAW264.7. We found that the lethal toxin and theExpand
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Theiler's virus replication in brain macrophages cultured in vitro.
Infection of the mouse with Theiler's virus is one of the best animal models for the study of multiple sclerosis, a chronic demyelinating disease of the human central nervous system. TheExpand
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Effects of antimitotic treatment on haematopoietic tissues in mice.
The antimitotic drug hydroxyurea was injected into mice twice daily for one, two, three or four consecutive days, and its effects assessed in bone marrow (BM) and spleen (SP). The number of nucleatedExpand
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