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Sarasinoside A1: a saponin containing amino sugars isolated from a sponge
(Z)- and (E)-2-((hydroxymethyl)cyclopropylidene)methyladenine and -guanine. New nucleoside analogues with a broad-spectrum antiviral activity.
Several Z-(hydroxymethyl)methylenecyclopropanes exhibited in vitro antiviral activity in micromolar or submicromolar range against human and murine cytomegalovirus (HCMV and MCMV), Epstein-Barr virus (EBV), human herpes virus 6 (HHV-6), varicella zoster virus (VZV), and hepatitis B virus (HBV).
Cyclic peptides from the ascidian Lissoclinum patella: conformational analysis of patellamide D by X-ray analysis and molecular modeling
Minabeolides: a group of withanolides from a soft coral, Minabea sp.
Three new C 28 and five C 27 steroidal lactones of the withanolide class have been isolated from a soft coral, Minabea sp., collected in Truk Lagoon. All the new lactones differ from the conventional…
(Z)‐ and (E)‐2‐((Hydroxymethyl)cyclopropylidene)methyladenine and ‐guanine. New Nucleoside Analogues with a Broad‐Spectrum Antiviral Activity.
Conformational analysis of an alpha-galactosyl trisaccharide epitope involved in hyperacute rejection upon xenotransplantation.
Caparratriene, an active sesquiterpene hydrocarbon from Ocotea caparrapi.
Caparratriene (1), a new sesquiterpene hydrocarbon with significant growth inhibitory activity (IC50 = 3.0 +/- 0.5 x 10(-6) M) against CEM leukemia cells, was isolated from the oil of Ocotea…
Pouosides A-E, novel triterpene galactosides from a marine sponge, Asteropus sp [Erratum to document cited in CA109(11):89977p]
Investigation of the adducts formed by reaction of malondialdehyde with adenosine.
The structure of M3A is investigated and a new structure is proposed which is tentatively named 6(5*,7*-diformyl-2*H-3*,6-dihydro-2*,6*-methano-1*,3-oxazocin -3*-yl)-9-beta-D-ribofuranosylpurine, which suggests they arise by reaction of the nucleoside bases with oligomers of MDA.
Arylamination and arylation of 4,4,4-trifluoro-1-phenyl-1,3-butanedione with N-acetoxy derivatives of 2-aminofluorene.
- C. Y. Wang, H. Nagase, M. Lee, M. Ksebati
- Chemistry, BiologyChemical research in toxicology
- 1 March 1992
The inhibitions by beta-diketones of nucleic acid-binding and bacterial mutagenesis of carcinogens are likely due to their trapping of the carcinogens.