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An improved method for the preparation of Streptomycetes and Micromonospora protoplasts.
Letter: Microbial semi-synthesis of aminoglycosidic antibiotics by mutants of S. ribosidificus and S. kanamyceticus.
Studies on a new nucleoside antibiotic, dapiramicin. I. Producing organism, assay method and fermentation.
- T. Shomura, N. Nishizawa, +6 authors S. Inouye
- Biology, Medicine
- The Journal of antibiotics
- 1 October 1983
Two assay methods for dapiramicin were developed, HPLC and a new bioassay by growth inhibition of fungal mycelia on a slide glass, which described the isolated antibiotic from the fermentation broth of Micromonospora sp. Expand
Dactylosporangium fulvum sp. nov.
A new species of the genus Dactylosporangium is described, which differs significantly from previously described species in its cultural and physiological characteristics. Expand
Studies on the Biosynthesis of Kanamycins
Streptomyces kanamyceticus produces 14C-kanamycin and other labeled kanamycin-related compounds in the presence of 14C-glucose or 14C-glucosamine. One of the latter is paromamine. In order to find a… Expand
Studies on the Biosynthesis of Kanamycins:Part II. Incorporation of the Radioactive Degradation Products of Kanamycin A or Related Metabolities into Kanamycin A
Incorporation of the radioactive degradation products of kanamycin A or related metabolites into kanamycin A by growing cells of Streptomyces kanamyceticus was examined. 3H-Deoxystreptamine was… Expand
13C-NMR studies on ribostamycin and its related compounds.
The 13C-NMR spectra of ribostamycin and its related compounds were measured, and the correlation of chemical shifts and structures was discussed. With the aid of the 13C-NMR technique, the structures… Expand
A new antibiotic SF-2370 produced by Actinomadura.
The isolation, characterization, and structural elucidation by the spectral studies are reported on a new indolocarbazole antibiotic SF-2370 which was isolated from a soil sample collected at Shimizu, Shizuoka Prefecture, Japan. Expand
Studies on the biosynthesis of bialaphos (SF-1293). 1. Incorporation of 13C- and 2H-labeled precursors into bialaphos.
The biosynthetic studies on I, a tripeptide comprising two alanine residues and one phosphinothricin, showed an AB-type 13C-13C coupling between C-4 and C-3 providing unequivocal evidence that these two carbon atoms in II originate from the intact acetic acid molecule. Expand