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Genetic and antigenic characterization of novel pestivirus genotypes: implications for classification.
TLDR
Taking into account the host origin, the lack of differences concerning the course of disease, and the results of the genetic and antigenic analyses, it is suggested that BDV-1, BDv-2, andBDV-3 should be considered as major genotypes within the species BDV. Expand
Phylogenetic analysis of pestiviruses from domestic and wild ruminants.
TLDR
The phylogenetic analysis strongly suggests that genotype 1 pestiviruses occur world-wide in many ruminant species, and phylogenetic trees based on the Npro gene nucleotide sequences show that the respective sequences do not segregate into discrete lineages based on host-species origin. Expand
Detection of Canine Distemper Virus Nucleoprotein RNA by Reverse Transcription-PCR Using Serum, Whole Blood, and Cerebrospinal Fluid from Dogs with Distemper
TLDR
Although the sensitivity of the RT-PCR for detection of CDV is strongly influenced by the location of the selected primers, this nucleic acid detection system represents a highly specific and sensitive method for the antemortem diagnosis of Distemper in dogs, regardless of the form of distemper, humoral immune response, and viral antigen distribution. Expand
Budding of Rabies Virus Particles in the Absence of the Spike Glycoprotein
TLDR
It is found that spikeless rhabdovirus particles were released from cells infected with the G-deficient mutant, demonstrating that a viral surface protein is not required to drive the budding process and that G also possesses an intrinsic and independent exocytosis activity. Expand
Genetic diversity of pestiviruses: identification of novel groups and implications for classification.
TLDR
The complete Npro coding sequences were determined for 16 pestiviruses isolated from cattle, pig, and several wild ruminant species including reindeer, bison, deer, and bongo, and Interestingly, the isolates from reindeers and bison are distinct from the established pestivirus species. Expand
Detection of Viral Proteins after Infection of Cultured Hepatocytes with Rabbit Hemorrhagic Disease Virus
TLDR
The calicivirus rabbit hemorrhagic disease virus (RHDV), which replicates predominantly in the livers of infected rabbits, cannot be propagated in tissue culture, so a refined model of RHDV genome organization is presented. Expand
Classical swine fever virus: independent induction of protective immunity by two structural glycoproteins
TLDR
Glycoprotein E0 represents a second determinant for the induction of protective immunity against classical swine fever and is detected on the surfaces of VVR-infected cells. Expand
Classical swine fever virus-specific cytotoxic T lymphocytes and identification of a T cell epitope.
TLDR
The sequence ENALLVALF is the first sequence to be identified as an MHC class I-restricted T cell epitope recognized by CSFV-specific CTL. Expand
Persistence of Bovine Viral Diarrhea Virus Is Determined by a Cellular Cofactor of a Viral Autoprotease
TLDR
It is described that a cellular chaperone termed Jiv (J-domain protein interacting with viral protein) acts as a cofactor of the NS2 protease, which is essential for maintenance of the noncytopathogenic phenotype of the virus and thereby for its ability to establish persistent infections. Expand
Pathogenesis of classical swine fever: B-lymphocyte deficiency caused by hog cholera virus
TLDR
It is shown here that the end stage of lethal infection in the natural host is associated with a dramatic depletion preferentially of B lymphocytes in the circulatory system as well as in lymphoid tissues. Expand
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