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Downregulation of melanin synthesis by haginin A and its application to in vivo lightening model.
  • J. Kim, S. Baek, +6 authors C. Lee
  • Biology, Medicine
  • The Journal of investigative dermatology
  • 1 May 2008
Haginin A, an isoflav-3-ens isolated from the branch of Lespedeza cyrtobotrya, is almost unknown. Here, we report that haginin A exhibits a strong hypopigmentary effect in Melan-a cells andExpand
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Neuroprotective action of N-acetyl serotonin in oxidative stress-induced apoptosis through the activation of both TrkB/CREB/BDNF pathway and Akt/Nrf2/Antioxidant enzyme in neuronal cells
N-acetyl serotonin (NAS) as a melatonin precursor has neuroprotective actions. Nonetheless, it is not clarified how NAS protects neuronal cells against oxidative stress. Recently, we have reportedExpand
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Optimized synthesis of 1,3-dioleoyl-2-palmitoylglycerol-rich triacylglycerol via interesterification catalyzed by a lipase from Thermomyces lanuginosus.
1,3-Dioleoyl-2-palmitoylglycerol (OPO)-rich human milk fat substitute (HMFS) was synthesized from tripalmitin-rich fraction and ethyl oleate by a lipase-catalyzed interesterification. ResponseExpand
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Prevention of 1-palmitoyl lysophosphatidylcholine-induced inflammation by polyunsaturated acyl lysophosphatidylcholine
ObjectiveThe aim of this study was to examine the inflammation induced by saturated acyl lysophosphatidylcholine (LPC) in vivo and to investigate whether it could be attenuated by the action ofExpand
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Rengyolone inhibits inducible nitric oxide synthase expression and nitric oxide production by down-regulation of NF-kappaB and p38 MAP kinase activity in LPS-stimulated RAW 264.7 cells.
Nitric oxide (NO) is recognized as a mediator and regulator of inflammatory responses. Rengyolone, a cyclohexylethanoid isolated from the fruits of Forsythia koreana, exhibits anti-inflammatoryExpand
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Genistein-derivatives from Tetracera scandens stimulate glucose-uptake in L6 myotubes.
An EtOAc-soluble partition of the MeOH extract of a branch of Tetracera scandens (Dilleniaceae family) was subjected to a glucose-uptake assay, which led to the isolation and identification of fiveExpand
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Hepatoprotective effect of aged black garlic on chronic alcohol-induced liver injury in rats.
The hepatoprotective effect of aged black garlic (ABG) against ethanol-induced oxidative liver damage was investigated in adult male Sprague-Dawley rats for 4 weeks. Rats were divided into threeExpand
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Antiatherogenic effects of structured lipid containing conjugated linoleic acid in C57BL/6J mice.
Conjugated linoleic acids (CLA) were enzymatically acidolyzed with olive oil to produce structured lipids (SL), and their antiatherosclerotic properties were investigated in C57BL/6J mice.Expand
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Protective effect of vegetable extracts on oxidative stress in brain of mice administered with NMDA
To find natural products showing a protective action against oxidative stress in the brain, extracts of various vegetables were administered i.p. with NMDA via gavage to ICR female mice. Changes inExpand
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Effect of endocannabinoids on IgE-mediated allergic response in RBL-2H3 cells.
Recently, some endocannabinoids were reported to show anti-inflammatory and anti-allergic activities. In this respect, various arachidonoyl endocannabinoids were screened for the inhibition ofExpand
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